918343-89-2Relevant academic research and scientific papers
A facile access to bridged 1,2,4-trioxanes
Zhang, Qi,Jin, Hong-Xia,Wu, Yikang
, p. 11627 - 11634 (2007/10/03)
Bicyclo[3.2.1] type 1,2,4-trioxanes are readily synthesized from precursors that may form intramolecular hemiketals using UHP (H2O2-urea complex) as the source of the peroxy bond and p-TsOH or CSA as the catalyst. The ring closure through an intramolecular Michael addition occurred in a highly stereoselective way, giving only one diasteromer as shown by the NMR spectra.
