918411-46-8 Usage
General Description
2S-7-Aza-bicyclo[2.2.1]heptane-2,7-dicarboxylic acid 7-tert-butyl ester is a chemical compound that belongs to the class of bicyclic compounds. It is an ester of 2S-7-azabicyclo[2.2.1]heptane-2,7-dicarboxylic acid, and the tert-butyl group is attached to the 7th position of the bicyclic ring. 2S-7-Aza-bicyclo[2.2.1]heptane-2,7-dicarboxylic acid 7-tert-butyl ester is commonly used in the field of organic chemistry as a building block or intermediate for the synthesis of various pharmaceuticals, agrochemicals, and other fine chemicals. Its unique structure and reactivity make it a valuable starting material for the production of diverse functionalized compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 918411-46-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,8,4,1 and 1 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 918411-46:
(8*9)+(7*1)+(6*8)+(5*4)+(4*1)+(3*1)+(2*4)+(1*6)=168
168 % 10 = 8
So 918411-46-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H19NO4/c1-12(2,3)17-11(16)13-7-4-5-9(13)8(6-7)10(14)15/h7-9H,4-6H2,1-3H3,(H,14,15)/t7-,8+,9+/m1/s1
918411-46-8Relevant articles and documents
Oligomers of β-amino acid bearing non-planar amides form ordered structures
Otani, Yuko,Futaki, Shiroh,Kiwada, Tatsuto,Sugiura, Yukio,Muranaka, Atsuya,Kobayashi, Nagao,Uchiyama, Masanobu,Yamaguchi, Kentaro,Ohwada, Tomohiko
, p. 11635 - 11644 (2006)
In this report, we explore the feasibility of using bicyclic chiral β-amino acids, (1R,2R,4S)- and (1S,2S,4R)-7-azabicyclo[2.2.1]heptane-2-carboxylic acid (R-Ah2c and S-Ah2c, respectively), to prepare novel peptides with unique properties. Facile cis-trans isomerization of the non-planar amide bonds of these β-amino acids should result in great flexibility of the backbone structure of β-peptides containing them. Indeed, oligomers of these amino acids showed thermostability and characteristic CD absorptions, which were not concentration-dependent, suggesting that the oligomers remained monomeric. The results indicated the formation of self-organized monomeric structures with chain-length-dependent stabilization. Energy calculations suggested that the peptides can take helical structures in which the energy barriers to cis-trans isomerization are greater for the central amide bonds than for the terminal amides.
