918415-58-4Relevant articles and documents
Efficient synthesis of new nucleoside analogues with a methylenecyclobutane unit
Danappe, Sophie,Boeda, Fabien,Alexandre, Christian,Aubertin, Anne-Marie,Bourgougnon, Nathalie,Huet, Francois
, p. 3225 - 3239 (2007/10/03)
Synthesis of eight nucleoside analogues 4-11 with a methylenecyclobutane unit is described. Wittig reaction with 2-hydroxymethylcyclobutanone 12 gave a mixture of Z (13) and E (14) derivatives, which was separated before functional modifications. The hete