91842-53-4

Basic information

• Product Name: 10-phenyl-3,6,9-trioxadecanoic acid
• Synonyms: 10-phenyl-3,6,9-trioxadecanoic acid;2-(2-(2-(benzyloxy)ethoxy)ethoxy)acetic acid;2-(2-(2-(benzyloxy)ethoxy)ethoxy)acetic acid(WXPC0027);BnO-PEG2-CH2COOH
• CAS NO: 91842-53-4
• Molecular Formula: C₁₃H₁₈O₅
• Molecular Weight: 254.27902
• Mol File: 91842-53-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 409.7±30.0 °C(Predicted)
• Appearance: /
• Density: 1.163±0.06 g/cm3(Predicted)
• PKA: 3.39±0.10(Predicted)
• CAS DataBase Reference: 10-phenyl-3,6,9-trioxadecanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 10-phenyl-3,6,9-trioxadecanoic acid(91842-53-4)
• EPA Substance Registry System: 10-phenyl-3,6,9-trioxadecanoic acid(91842-53-4)

Safety Data

• Hazardous Substances Data: 91842-53-4(Hazardous Substances Data)

Usage

Class

Oxecarboxylic acids

Physical state

White crystalline solid

Molecular weight

344.406 g/mol

Applications

a. Precursor in the synthesis of other organic compounds and materials
b. Production of polymers
c. Production of resins
d. Production of pharmaceuticals

Biological and environmental effects

Not known to have any significant effects

Stability

Relatively stable under normal conditions

Safety precautions

Proper handling and disposal procedures should be followed to minimize potential risks associated with its use.

Upstream product

• 55489-58-2 triethylene glycol monobenzyl ether 
• 2050-25-1 diethylene glycol monobenzyl ether 
• 79-11-8 chloroacetic acid 

Downstream Products

• 1192068-66-8 3-{2-[2-(2-benzyloxyethoxy)ethoxy]acetoxy}-(S)-2-((S)-2-tert-butoxycarbonylaminothiopropionylamino)propionic acid tert-butyl ester 
• 314770-76-8 10-phenyl-3,6,9-trioxadecanoic acid 2-(trimethylsilyl)ethyl ester 
• 91842-54-5 N-benzyl-N-ethyl-10-phenyl-3,6,9-trioxadecanamide 
• 91842-55-6 N-benzyl-N-ethyl-(10-phenyl-3,6,9-trioxadecyl)amine 
• 91842-59-0 N-ethyl(10-phenyl-3,6,9-trioxadecyl)amine 

Relevant articles and documents

Influence of Linker Attachment Points on the Stability and Neosubstrate Degradation of Cereblon Ligands

Proteolysis targeting chimeras (PROTACs) hijacking the cereblon (CRBN) E3 ubiquitin ligase have emerged as a novel paradigm in drug development. Herein we found that linker attachment points of CRBN ligands highly affect their aqueous stability and neosubstrate degradation features. This work provides a blueprint for the assembly of future heterodimeric CRBN-based degraders with tailored properties.

METHODS AND REAGENTS MAKING MULTIVALENT ARRAYS AND COMBINATORIAL LIBRARIES OF MULTIVALENT ARRAYS

Methods of preparing libraries of multivalent arrays and libraries made by the methods. Component multivalent arrays of a library have defined length, defined terminal functionality and defined pendant functional groups. Methods include the preparation of

Effect of Amines on O-Benzyl Group Hydrogenolysis

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