918423-58-2

Upstream product

• 205999-81-1 (+)-(3R,4R)-4-(3-(benzyloxy)phenyl)-3,4-dimethylpiperidine 
• 918423-54-8 1-((2S,4R,5R)-2-allyl-4-(3-benzyloxy-phenyl)-4,5-dimethyl-piperidin-1-yl)prop-2-en-1-one 
• 918423-38-8 (2S,4R,5R)-2-allyl-4-(3-benzyloxy-phenyl)-4,5-dimethyl-piperidin-1-ol 
• 918423-40-2 (2S,4R,5R)-2-allyl-4-(3-(benzyloxy)phenyl)-4,5-dimethyl-piperidine 
• 918423-56-0 (7R,8R,9aS)-8-(3-(benzyloxy)phenyl)-7,8-dimethyl-7,8,9,9a-tetrahydro-1H-quinolizin-4(6H)-one 

Relevant academic research and scientific papers

Elucidation of the bioactive conformation of the N-substituted trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine class of μ-opioid receptor antagonists

The series of trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines have been widely investigated as opioid receptor antagonists. One of our research goals was to explore the bioactive conformation of the N-phenethyl trans-3,4-dimethyl-4-(3-hydroxyphenyl)pipe