918501-86-7

Basic information

• Product Name: 1-Piperidinecarboxylic acid, 4-[(4-chlorophenyl)[(methylsulfonyl)oxy]methyl]-, 1,1-dimethylethyl ester
• CAS NO: 918501-86-7
• Molecular Formula: C18H26ClNO5S
• Molecular Weight: 403.927
• Mol File: 918501-86-7.mol

Chemical Properties

• CAS DataBase Reference: 1-Piperidinecarboxylic acid, 4-[(4-chlorophenyl)[(methylsulfonyl)oxy]methyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperidinecarboxylic acid, 4-[(4-chlorophenyl)[(methylsulfonyl)oxy]methyl]-, 1,1-dimethylethyl ester(918501-86-7)
• EPA Substance Registry System: 1-Piperidinecarboxylic acid, 4-[(4-chlorophenyl)[(methylsulfonyl)oxy]methyl]-, 1,1-dimethylethyl ester(918501-86-7)

Safety Data

• Hazardous Substances Data: 918501-86-7(Hazardous Substances Data)

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 639468-65-8 4-[(4-chlorophenyl)hydroxymethyl]piperidine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 918501-87-8 C₁₇H₂₃ClN₄O₂ 

Relevant articles and documents

Carbon-linked substituted piperidines and derivatives thereof useful as histamine H3 antagonists

Disclosed are compounds of the formula or a pharmaceutically acceptable salt thereof, wherein: M1 and M3 are CH or N; M2 is CH, CF or N; Y is —C(═O)—, —C(═S)—, —(CH2)q—, —C(═NOR7)— or —SO1-2—; Z is a bond or optionally substituted alkylene or alkenylene; R1 is H, alkyl, alkenyl, or optionally substituted cycloalkyl, aryl, heteroaryl, heterocycloalkyl or a group of the formula: where ring A is a monoheteroaryl ring; R1 is optionally substituted alkyl, alkenyl, aryl, heteroaryl, cycloalkyl or heterocycloalkyl; and the remaining variables are as defined in the specification; compositions and methods of treating allergy-induced airway responses, congestion, obesity, metabolic syndrome nonalcoholic fatty liver disease, hepatic steatosis, nonalcoholic steatohepatitis, cirrhosis, hepatacellular carcinoma or cognition deficit disorders using said compounds, alone or in combination with other agents.