918525-02-7 Usage
Uses
Used in Organic Synthesis:
3-Bromo-1-[tris(1-methylethyl)silyl]-1H-pyrrolo[2,3-b]pyridine is used as a building block in organic synthesis for the preparation of pharmaceuticals, agrochemicals, and functional materials. Its unique structure and reactivity contribute to the development of new drugs and materials with enhanced properties.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 3-Bromo-1-[tris(1-methylethyl)silyl]-1H-pyrrolo[2,3-b]pyridine is used as a key intermediate in the synthesis of new drugs. Its potential applications in drug development are attributed to its ability to form various chemical entities with therapeutic properties.
Used in Agrochemical Development:
3-Bromo-1-[tris(1-methylethyl)silyl]-1H-pyrrolo[2,3-b]pyridine is also utilized in the agrochemical industry for the development of new pesticides and other crop protection agents. Its unique chemical properties can be harnessed to create effective and environmentally friendly agrochemicals.
Used as a Protecting Group in Chemical Reactions:
The tris(1-methylethyl)silyl group in 3-Bromo-1-[tris(1-methylethyl)silyl]-1H-pyrrolo[2,3-b]pyridine can serve as a protecting group for sensitive functional groups during chemical reactions. This feature is particularly useful in the synthesis of complex organic molecules, where the protection and subsequent deprotection of functional groups are crucial for achieving the desired product.
Check Digit Verification of cas no
The CAS Registry Mumber 918525-02-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,8,5,2 and 5 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 918525-02:
(8*9)+(7*1)+(6*8)+(5*5)+(4*2)+(3*5)+(2*0)+(1*2)=177
177 % 10 = 7
So 918525-02-7 is a valid CAS Registry Number.
918525-02-7Relevant academic research and scientific papers
A closer look at the bromine-lithium exchange with tert-butyllithium in an aryl sulfonamide synthesis
Waldmann, Christopher,Schober, Otmar,Haufe, Guenter,Kopka, Klaus
supporting information, p. 2954 - 2957 (2013/07/26)
A practical protocol for the one-pot synthesis of various aryl sulfonamides, notably of pyridine-core-substituted 7-azaindolyl sulfonamides, is described. A key step is the well-known bromine-lithium exchange reaction of an aryl bromide with tert-butyllithium (t-BuLi). Differing from the common practice to use 2 or more equiv of organolithium, the exact amount of t-BuLi needed for a sufficient exchange reaction is determined for each aryl bromide in a GC-MS-assisted experiment.
