918540-55-3

Basic information

• Product Name: 2-Butanone, 4-(4-iodophenyl)-
• Synonyms: 4-(4-iodophenyl)-2-butanone;2-Butanone,4-(4-iodophenyl)
• CAS NO: 918540-55-3
• Molecular Formula: C10H11IO
• Molecular Weight: 274.101
• Mol File: 918540-55-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-Butanone, 4-(4-iodophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butanone, 4-(4-iodophenyl)-(918540-55-3)
• EPA Substance Registry System: 2-Butanone, 4-(4-iodophenyl)-(918540-55-3)

Safety Data

• Hazardous Substances Data: 918540-55-3(Hazardous Substances Data)

Upstream product

• 54589-53-6 4-iodobenzyl chloride 
• 123-54-6 acetylacetone 
• 598-32-3 2-hydroxy-3-butene 
• 16004-15-2 1-bromomethyl-4-iodobenzene 

Downstream Products

• 939825-20-4 1-bromo-4-(4-iodophenyl)-2-butanone 
• 700349-21-9 4-(4-iodophenyl)-2-methyl-2-butanol 
• 2351-50-0 4-iodostyrene 
• 939825-23-7 1-(1H-imidazol-1-yl)-4-(4-iodophenyl)-2-butanone 
• 958640-38-5 4-(4-iodophenyl)-2-methyl-2-trimethylsiloxybutane 

Relevant articles and documents

BENZYL-, (PYRIDIN-3-YL)METHYL- OR (PYRIDIN-4-YL)METHYL-SUBSTITUTED OXADIAZOLOPYRIDINE DERIVATIVES AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS

The present invention relates to compounds of general formula (I), wherein the groups R1 and R2 are defined as in claim 1, which have valuable pharmacological properties, in particular bind to ghrelin O-acyl transferase (GOAT) and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular obesity.

InCl3-catalyzed cross-coupling of alkyl trimethylsilyl ethers and allylsilanes via an in situ derived combined lewis acid of InCl3 and Me3SiI

(Chemical Equation Presented) Direct Csp3-Csp3 coupling of various aliphatic trimethylsilyl ethers and allylsilanes is effectively catalyzed by InCl3 and I2. The transformation is thought to involve an in situ-derived combined Lewis acid of InCl3 and Me3SiI. The reaction can be used for the construction of quaternary-quaternary and quaternary-tertiary carbon-carbon bonds. This system enabled a highly chemoselective coupling to be conducted with a trimethylsilyl ether including an aryl halide moiety. Furthermore, couplings were possible using an alkynyltri-methylsilane and a trimethylsilyl ketene acetal.

Arenediazonium o-benzenedisulfonimides in Heck-type arylation of allylic alcohols

Arenediazonium o-benzenedisulfonimides were reacted with primary and secondary allylic alcohols. The reactions, carried out in aqueous ethanol in the presence of palladium(II) acetate as precatalyst and sodium hydrogen carbonate as base, gave the arylation products with good overall conversion. In all cases, the major products were the β-arylated carbonyl derivatives. The o-benzene-disulfonimide was recovered in high yield from all the reactions, and it was recycled for the preparation of other salts. Georg Thieme Verlag Stuttgart.