54589-53-6

Basic information

• Product Name: p-Iodobenzylchloride
• Synonyms: p-Iodobenzylchloride
• CAS NO: 54589-53-6
• Molecular Formula: C₇H₆ClI
• Molecular Weight: 252.48
• Mol File: 54589-53-6.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: p-Iodobenzylchloride(CAS DataBase Reference)
• NIST Chemistry Reference: p-Iodobenzylchloride(54589-53-6)
• EPA Substance Registry System: p-Iodobenzylchloride(54589-53-6)

Safety Data

• Hazardous Substances Data: 54589-53-6(Hazardous Substances Data)

Upstream product

• 19028-26-3 4-dichloroiodanyl-toluene 
• 18282-51-4 4-iodo-benzyl alcohol 
• 10026-13-8 phosphorus pentachloride 
• 873-75-6 4-bromobenzenemethanol 
• 624-31-7 4-tolyl iodide 
• 876-08-4 p-(chloromethyl)benzoyl chloride 
• 100-44-7 benzyl chloride 
• 50-00-0 formaldehyd 
• 591-50-4 iodobenzene 

Downstream Products

• 60599-65-7 phosphoric acid tris-(4-iodo-benzyl ester) 
• 39959-59-6 4-iodobenzyl amine 
• 51628-12-7 4-iodophenylacetonitrile 
• 54759-14-7 1-Phenoxy-4-[(4'-iodo)-benzyloxy]benzene 
• 958640-38-5 4-(4-iodophenyl)-2-methyl-2-trimethylsiloxybutane 
• 700349-21-9 4-(4-iodophenyl)-2-methyl-2-butanol 
• 1357918-77-4 (4-(chloromethyl)phenyl)iodanediyl diacetate 
• 1357918-15-0 (4-chloromethylphenyl)(4’-methoxyphenyl)iodonium tosylate 
• 1357918-36-5 (4-chloromethylphenyl)(2’,4’,6’-trimethoxyphenyl)iodonium tosylate 
• 59528-27-7 p-iodobenzylamine hydrochloride 

Relevant articles and documents

1-methyl-3-(4-diacetoxyl iodobenzene methyl) imidazole chlorine salt as well as preparation and application thereof

The invention discloses 1-methyl-3-(4-diacetoxyl iodobenzene methyl) imidazole chlorine salt as well as preparation and application thereof. The structure of the 1-methyl-3-(4-diacetoxyl iodobenzene methyl) imidazole chlorine salt is shown in the specification. The invention provides application of the 1-methyl-3-(4-diacetoxyl iodobenzene methyl) imidazole chlorine salt as a gold leaching agent. The application comprises the following steps: putting a sample with a noble metal into the 1-methyl-3-(4-diacetoxyl iodobenzene methyl) imidazole chlorine salt, and performing sufficient stirring so as to leach the noble metal. The 1-methyl-3-(4-diacetoxyl iodobenzene methyl) imidazole chlorine salt which is disclosed by the invention has good capabilities of oxidation and metal coordination, canbe used as the gold leaching agent, breaks through the defect that a toxic gold leaching agent is used in the conventional metallurgical industry, and has the advantages of being efficient, green andenvironment-friendly and sustainable.

Halogenation through Deoxygenation of Alcohols and Aldehydes

An efficient reagent system, Ph3P/XCH2CH2X (X = Cl, Br, or I), was very effective for the deoxygenative halogenation (including fluorination) of alcohols (including tertiary alcohols) and aldehydes. The easily available 1,2-dihaloethanes were used as key reagents and halogen sources. The use of (EtO)3P instead of Ph3P could also realize deoxy-halogenation, allowing for a convenient purification process, as the byproduct (EtO)3Pa?O could be removed by aqueous washing. The mild reaction conditions, wide substrate scope, and wide availability of 1,2-dihaloethanes make this protocol attractive for the synthesis of halogenated compounds.

The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactors

Herein we describe the application of a monolithic triphenylphosphine reagent to the Appel reaction in flow-chemistry processi to generate various brominated products with high purity and in excellent yields, and with no requirement for further off-line pu fication.