91857-86-2

Basic information

• Product Name: 1H-Pyrazol-4-amine, 3-phenyl-
• Synonyms: 1H-Pyrazol-4-amine, 3-phenyl-;5-phenyl-1H-pyrazol-4-amine(SALTDATA: FREE);5-phenyl-1H-pyrazol-4-amine 2HCl H2O;3-Phenyl-1H-pyrazol-4-amine
• CAS NO: 91857-86-2
• Molecular Formula: C₉H₉N₃
• Molecular Weight: 159.19
• Mol File: 91857-86-2.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 1H-Pyrazol-4-amine, 3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazol-4-amine, 3-phenyl-(91857-86-2)
• EPA Substance Registry System: 1H-Pyrazol-4-amine, 3-phenyl-(91857-86-2)

Safety Data

• Hazardous Substances Data: 91857-86-2(Hazardous Substances Data)

Usage

Structure

A derivative of pyrazole, a five-membered aromatic heterocycle containing two nitrogen atoms, with a phenyl group attached to the 3-position of the pyrazole ring.

Usage

Commonly used as a pharmaceutical intermediate in the synthesis of various biologically active compounds.

Application

Can be used as a research tool in the study of pyrazole derivatives and their potential pharmacological properties.

Interest

Of interest in the fields of medicinal chemistry and drug development due to its versatile nature and potential applications.

Upstream product

• 536-74-3 phenylacetylene 
• 30159-39-8 4-(3-phenyl-pyrazol-1-yl)-morpholine 
• 70-11-1 α-bromoacetophenone 
• 532-27-4 1-chloroacetophenone 
• 1032-67-3 N-benzoylmethylphthalimide 
• 216854-27-2 2-(3-phenyl-1H-pyrazol-4-yl)isoindoline-1,3-dione 

Downstream Products

• 113140-16-2 7-chloro-5-methyl-3-phenyl-2H-pyrazolo[4,3-b]pyridine 

Relevant articles and documents

COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY

This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt, and/or hydrate, and/or cocrystal, and/or drug combination of the compound) that inhibit (e.g., antagonize) Stimulator of Interferon Genes (STING). Said chemical entities are useful, e.g., for treating a condition, disease or disorder in which increased (e.g., excessive) STING activation (e.g., STING signaling) contributes to the pathology and/or symptoms and/or progression of the condition, disease or disorder (e.g., cancer) in a subject (e.g., a human). This disclosure also features compositions containing the same as well as methods of using and making the same.

Synthesis of 3-phenylpyrazolo[4,3-b]pyridines via a convenient synthesis of 4-amino-3-arylpyrazoles and SAR of corticotropin-releasing factor receptor type-1 antagonists

3-Phenylpyrazolo[4,3-b]pyridines were synthesized via a cyclization of 4-amino-3-phenylpyrazoles 11-13 with ethyl acetoacetate. These compounds were found to be potent CRF1 antagonists. The 2-alkylpyrazolo[4,3-b]pyridines were more polar but le

Synthesis and reaction of 1 (N,N disubstituted amino) pyrazoles

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