91870-98-3

Upstream product

• 29026-66-2 spiro<1,3-benzoxathiole-2,1'-cyclohexane> 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 

Downstream Products

• 99-93-4 4-Hydroxyacetophenone 

Relevant academic research and scientific papers

Studies on the Synthesis of Heterocyclic Compounds. XVI. Cleavage of 1,3-Benzodioxoles and -Benzoxathioles by Sodium Iodide-Acyl Chloride

The cleavage reaction of ethereal and thioethereal bonds with sodium iodide and acyl chloride has been studied.In all the 1,3-benzodioxoles and -benzoxathioles studied, the opening of the heterocyclic ring with formation of 1,2-diacetoxybenzene or 2-hydroxythiophenol diacetic acid ester and gem-diiodoalkanes and iodoalkenes has been observed.The structure of newly prepared compounds has been determined by analytical and spectroscopic data or comparison with authentic samples.

On the Acylation of 1,3-Benzoxathiole Systems

The acylation on 1,3-benzoxathiole systems, as well as the effect of the stoichiometry of the catalyst on the yields of ketones and of breaking products of the O-C-S bonds is here described.

Studies on the Synthesis of Heterocyclic Compounds. XIV. Cleavage of 1,3-Benzoxathioles by Magnesium Bromide-Acetic Anhydride

The cleavage reaction of some 1,3-benzoxathioles with magnesium bromide and acetic anhydride has been studied.In all the 1,3-benzoxathioles studied, the opening of the heterocyclic ring occurs first with cleavage of the C-O bond and formation of bromides and their corresponding products of hydrolysis.Successively also the cleavage of the C-S bond can occur.The competitive electrophilic substitution on the benzene ring becomes appreciable only in the 1,3-benzoxathioles-2,2-disubstituted with sterically demanding groups.The structure of newly prepared compounds has been determined by analytical and spectroscopic data and when possible by comparison with authentic samples.