918797-45-2Relevant academic research and scientific papers
High antiplasmodial activity of novel plasmepsins I and II inhibitors
Dell'Agli, Mario,Parapini, Silvia,Galli, Germana,Vaiana, Nadia,Taramelli, Donatella,Sparatore, Anna,Liu, Peng,Dunn, Ben M.,Bosisio, Enrica,Romeo, Sergio
, p. 7440 - 7449 (2007/10/03)
The aim of this study was to develop new antiplasmodial compounds acting through distinct mechanisms during both the liver and the blood stages of the parasite life cycle. Compounds were designed on the basis of the "double-drug" approach: primaquine, whi
