918809-06-0Relevant academic research and scientific papers
Design and synthesis of phenylpyrrolidine phenylglycinamides as highly potent and selective TF-FVIIa inhibitors
Zhang, Xiaojun,Jiang, Wen,Jacutin-Porte, Swanee,Glunz, Peter W.,Zou, Yan,Cheng, Xuhong,Nirschl, Alexandra H.,Wurtz, Nicholas R.,Luettgen, Joseph M.,Rendina, Alan R.,Luo, Gang,Harper, Timothy M.,Wei, Anzhi,Anumula, Rushith,Cheney, Daniel L.,Knabb, Robert M.,Wong, Pancras C.,Wexler, Ruth R.,Priestley, E. Scott
, p. 188 - 192 (2014/03/21)
Inhibitors of the Tissue Factor/Factor VIIa (TF-FVIIa) complex are promising novel anticoagulants that show excellent efficacy and minimal bleeding in preclinical models. On the basis of a zwitterionic phenylglycine acylsulfonamide 1, a phenylglycine benz
