91918-90-0

Usage

General Description

8-hydrazinyl-6-methyl[1,3]dioxolo[4,5-g]quinoline is a chemical compound that belongs to the quinoline class. It contains a hydrazine functional group at the 8 position and a methyl group at the 6 position, as well as a dioxolo ring fused to the quinoline ring system. 8-hydrazinyl-6-methyl[1,3]dioxolo[4,5-g]quinoline may have potential applications in the field of medicinal chemistry and drug discovery due to its unique structure and potential biological activities. However, further research is needed to explore its properties and potential uses in various fields.

Upstream product

• 50593-65-2 6-metil-8-cloro-1,3-diossol<4,5-g>chinolina 
• 50593-64-1 6-metil-8-ossi-1,3-diossol<4,5-g>chinolina 
• 91918-88-6 β-(3,4-metilendiossifenilammino)crotonato di etile 
• 14268-66-7 benzo[1,3]dioxolo-5-ylamine 

Downstream Products

• 91919-09-4 NSC332397 
• 91919-02-7 NSC332389 
• 91918-93-3 N-[1-(4-Chloro-phenyl)-meth-(E)-ylidene]-N'-(6-methyl-[1,3]dioxolo[4,5-g]quinolin-8-yl)-hydrazine 
• 91918-97-7 NSC₃₃₂₃₈₄ 
• 91918-97-7 C₁₉H₁₇N₃O₃ 
• 1392812-58-6 4-nitro-N'-(6-methyl-2H-[1,3]dioxolo[4,5-g]quinolin-8-yl)benzohydrazide 
• 1392812-73-5 2-(2,4-bis(trifluoromethyl)benzylidene)-1-(6-methyl-2H-[1,3]dioxolo[4,5-g]quinolin-8-yl)hydrazine 
• 1392812-62-2 methyl 4-[(2-{6-methyl-2H-[1,3]dioxolo[4,5-g]quinolin-8-yl}hydrazin-1-ylidene)methyl]benzoate 
• 1392812-75-7 2-(4-carboxybenzylidene)-1-(6-methyl-2H-[1,3]dioxolo[4,5-g]quinolin-8-yl)hydrazine 
• 1392812-70-2 2-(2-nitrobenzylidene)-1-(6-methyl-2H-[1,3]dioxolo[4,5-g]quinolin-8-yl)hydrazine 
• 1392812-68-8 2-(4-methanesulfonamidobenzylidene)-1-(6-methyl-2H-[1,3]dioxolo[4,5-g]quinolin-8-yl)hydrazine 
• 1392812-64-4 2-(4-(methylthio)benzylidene)-1-(6-methyl-2H-[1,3]dioxolo[4,5-g]quinolin-8-yl)hydrazine 
• 1392812-57-5 N-(4-nitrobenzylidene)-N-(6-methyl-2H-[1,3]dioxolo[4,5-g]quinolin-8-yl)amine 
• 1392812-56-4 (E)-6-methyl-8-(2-(1-(4-nitrophenyl)ethylidene)hydrazinyl)-2H-[1,3]dioxolo[4,5-g]quinoline 

Relevant academic research and scientific papers

Microwave-assisted synthesis of 4-quinolylhydrazines followed by nickel boride reduction: a convenient approach to 4-aminoquinolines and derivatives

Nickel(II) chloride/sodium borohydride combination was employed for the reduction of 4-hydrazinoquinoline derivatives to the corresponding anilines. This reductive protocol was efficiently applied for the reductive cleavage of monosubstituted hydrazines. We described herein the microwave-assisted synthesis of 4-hydrazinoquinolines, which furnished a high yielding and rapid two-step procedure for the synthesis, under mild conditions, of 4-aminoquinolines as antimalarial precursors.

SINTESI ED ATTIVITA BIOLOGICA DI NUOVI COMPOSTI A STRUTTURA 1,3-DIOSSOL CHINOLINICA

The synthesis of some 1,3-dioxol quinoline derivatives is described.The compounds show appreciable activity in vitro against P388 lymphocytic leukemia.Microbiological and antitumor results are presented.