50593-65-2Relevant academic research and scientific papers
Potent DNA-directed alkylating agents: Synthesis and biological activity of phenyl N-mustard-quinoline conjugates having a urea or hydrazinecarboxamide linker
Kakadiya, Rajesh,Dong, Huajin,Kumar, Amit,Narsinh, Dodia,Zhang, Xiuguo,Chou, Ting-Chao,Lee, Te-Chang,Shah, Anamik,Su, Tsann-Long
supporting information; experimental part, p. 2285 - 2299 (2010/06/14)
A series of N-mustard-quinoline conjugates bearing a urea or hydrazinecarboxamide linker was synthesized for antitumor evaluation. The in vitro cytotoxicity studies revealed that compounds with hydrazinecarboxamide linkers were generally more cytotoxic th
SINTESI ED ATTIVITA BIOLOGICA DI NUOVI COMPOSTI A STRUTTURA 1,3-DIOSSOL CHINOLINICA
Pellerano, C.,Savini, L.
, p. 640 - 648 (2007/10/02)
The synthesis of some 1,3-dioxol quinoline derivatives is described.The compounds show appreciable activity in vitro against P388 lymphocytic leukemia.Microbiological and antitumor results are presented.
