919293-28-0Relevant academic research and scientific papers
Catalytic asymmetric conjugate addition of isocyanoacetate to (Z)-3-substituted-2-(4-pyridyl)-acrylonitrile, a reactive class of Michael acceptor
Del Fiandra, Claudia,Moccia, Maria,Cerulli, Valentina,Adamo, Mauro F. A.
, p. 1697 - 1700 (2016)
(Z)-3-Substituted-2-(4-pyridyl)-acrylonitriles, a reactive class of Michael acceptors obtained exclusively as a single (Z) isomer, reacted with un-substituted isocyanoacetate esters mediated by phase-transfer catalysis to give, after base promoted cyclisation, functionalized imines in up to 94% ee and as a single diastereoisomer.
Quantitative analysis of weak non-covalent interactions in (Z)-3-(4-halophenyl)-2-(pyridin-2/3/4-yl)acrylonitriles
Venkatesan, Perumal,Cerón, Margarita,Thamotharan, Subbiah,Robles, Fernando,Percino, M. Judith
, p. 2681 - 2697 (2018/05/28)
A detailed experimental and theoretical investigation on the intermolecular interactions in (Z)-3-(4-halophenyl)-2-(pyridin-2/3/4-yl)acrylonitriles is reported. The intermolecular interactions are analyzed and quantified by PIXEL, DFT and quantum theory o
