13121-99-8

Basic information

• Product Name: PYRIDIN-4-YL-ACETONITRILE
• Synonyms: RARECHEM AK ML 0204;PYRIDIN-4-YL-ACETONITRILE;2-(Pyridin-4-yl)acetonitrile;Pyridine-4-yl-Acetonitrile;4-Pyridineacetonitrile;4-Pyridineacetonitrile, 97+%;2-(Pyridin-4-yl)
• CAS NO: 13121-99-8
• Molecular Formula: C₇H₆N₂
• Molecular Weight: 118.14
• Mol File: 13121-99-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: 52-53 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 258.8°C at 760 mmHg
• Flash Point: 99.3°C
• Appearance: /Solid
• Density: 1.085g/cm³
• Vapor Pressure: 0.0135mmHg at 25°C
• Refractive Index: 1.533
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 4.49±0.10(Predicted)
• Water Solubility: Slightly soluble in water.
• CAS DataBase Reference: PYRIDIN-4-YL-ACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: PYRIDIN-4-YL-ACETONITRILE(13121-99-8)
• EPA Substance Registry System: PYRIDIN-4-YL-ACETONITRILE(13121-99-8)

Safety Data

• HazardClass: 6.1
• Hazardous Substances Data: 13121-99-8(Hazardous Substances Data)

Usage

Uses

A pyridine derivative used in the preparation of inhibitors of Acyl CoA, cholesterol acyltransferase as well as bone morphogenetic protein (BMP) signaling inhibitors.

InChI:InChI=1/C7H6N2/c8-4-1-7-2-5-9-6-3-7/h2-3,5-6H,1H2

Upstream product

• 626-55-1 3-Bromopyridine 
• 75-05-8 acetonitrile 

Downstream Products

• 919293-28-0 (Z)-3-(4-bromophenyl)-2-(pyridin-4-yl)acrylonitrile 
• 148671-42-5 3-(4-fluorophenyl)-3-oxo-2-(pyridin-4-yl)propanenitrile 
• 216661-87-9 4-(4-pyridyl)-1H-pyrazol-3-amine 
• 518354-96-6 C₁₅H₁₃FN₄O 
• 518354-96-6 C₁₅H₁₃FN₄O 
• 55-22-1 pyridine-4-carboxylic acid 
• 103284-48-6 3-octyl-3-(4-pyrido)piperidine-2,6-dione 
• 103284-30-6 3-ethyl-1-octyl-3-(4-pyridyl)piperidine-2,6-dione 
• 103284-44-2 3-butyl-3-(4-pyridyl)piperidine-2,6-dione 
• 216661-58-4 3-(pyridin-4-yl)-6-(4-methoxyphenyl)-pyrazolo(1,5-A)pyrimidine 
• 216661-87-9 5-amino-4-(pyridin-4-yl)-1H-pyrazole 
• 349095-02-9 tert-butyl (3R)-3-[({[(Z)-1-amino-2-(4-pyridinyl)ethylidene]amino}oxy)carbonyl]-6-cyclohexylhexanoate 
• 751462-82-5 1-benzyl-4-(pyridin-4-yl)piperidine-4-carbonitrile 
• 13258-63-4 4-(2-Aminoethyl)pyridine 

Relevant articles and documents

NEW APPLICATION OF COMPLEX BASES: NUCLEOPHILIC CONDENSATIONS OF PYRIDINE

3,4-Dehydropyridine can be easily generated from 3-bromopyridine by complex bases.Nucleophilic condensations of amines, ketones and nitrile enolates are thus performed for the first time in good to very good yields.