91950-00-4

Upstream product

• 95-84-1 3-amino-4-hydroxytoluene 
• 814-68-6 acryloyl chloride 

Downstream Products

• 145600-96-0 2-[3-(4-benzhydrylpiperazino)propionyl]amino-4-methylphenol 
• 1025840-02-1 3-{4-[Bis-(4-chloro-phenyl)-methyl]-piperazin-1-yl}-N-(2-hydroxy-5-methyl-phenyl)-propionamide 
• 157020-44-5 2-<<3-<4-(diphenylmethoxy)-1-piperidinyl>propionyl>amino>-4-methylphenol 
• 1026940-01-1 3-{4-[(4-Chloro-phenyl)-phenyl-methyl]-[1,4]diazepan-1-yl}-N-(2-hydroxy-5-methyl-phenyl)-propionamide 
• 1027919-91-0 3-{4-[Bis-(4-fluoro-phenyl)-methoxy]-piperidin-1-yl}-N-(2-hydroxy-5-methyl-phenyl)-propionamide 
• 1026238-50-5 3-{4-[Bis-(4-fluoro-phenyl)-hydroxy-methyl]-piperidin-1-yl}-N-(2-hydroxy-5-methyl-phenyl)-propionamide 
• 1027545-58-9 3-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-1-yl}-N-(2-hydroxy-5-methyl-phenyl)-propionamide 
• 145600-66-4 2-[3-[4-(4,4'-dichlorobenzhydryl)piperazino]propyl]amino-4-methylphenol 
• 145600-69-7 2-[3-[4-(4,4'-difluorobenzhydryl)piperazino]propyl]amino-4-methylphenol 
• 145600-63-1 2-(3-{4-[(4-Chloro-phenyl)-hydroxy-phenyl-methyl]-piperidin-1-yl}-propylamino)-4-methyl-phenol 
• 145600-52-8 2-[3-[4-(4-chlorobenzhydryl)piperazino]propyl]amino-4-methylphenol 

Relevant academic research and scientific papers

N-AMIDE DERIVATIVES OF 8-AZABICYCLO[3.2.1]OCT-3-YL AS CCR1 ANTAGONISTS

The present invention relates to new antagonists of the interaction between the CCR1 Chemokine receptor and its ligands, including MIP-1α (CCL3), in particular new N-amide derivatives of 8-azabicyclo[3.2.1]oct-3-yl of formula (I).

Synthesis and topical antiinflammatory and antiallergic activities of antioxidant o-aminophenol derivatives

In order to develop novel compounds for topical use possessing antiallergic as well as antiinflammatory activities, a series of o- aminophenol derivatives bearing H1-antihistaminic structures were synthesized and their effects were investigated

Substituted or unsubstituted benzhydryl heteroalkyl-substituted aminophenol compounds and pharmaceutical compositions thereof

Aminophenol derivatives of the following formula (I) STR1 wherein X is hydrogen atom, lower alkyl or a protecting group for phenolic hydroxy, Y is hydrogen atom or lower alkyl, Z is hydrogen atom, lower alkyl, halogen atom or trifluoromethyl, A is hydrogen atom or lower alkyl, t is an integer of 1 to 5, l and m are respectively an integer of 2 to 4, E and W are nitrogen atoms, F is a direct bond or oxygen atom, P and Q are each hydrogen atom, halogen atom, lower alkyl or lower alkoxy, and R8 is hydrogen atom, hydroxy or a hydroxy-protecting group, and their pharmcologically acceptable salts. Since the aminophenol derivatives (I) of the present invention have excellent antioxidative action and antiinflammatory and antiallergic action in mammalian animals including human, they are extremely useful as pharmaceuticals such as an antiinflammatory or an antiallergic.