919518-65-3Relevant academic research and scientific papers
Total synthesis of tubulysin U and V
D?mling, Alexander,Beck, Barbara,Eichelberger, Uwe,Sakamuri, Sukumar,Menon, Sanjay,Chen, Quin-Zene,Lu, Yingchun,Wessjohann, Ludger A.
, p. 7235 - 7239 (2006)
Multicomponent method: Tubulysins are among the most potent cytotoxic agents known. Now the first total synthesis of some members has been achieved by utilizing a rapid three-component reaction for the synthesis of the unusual central thiazole amino acid
