91970-98-8Relevant academic research and scientific papers
Reexamen de la transposition de Fries des acetate et propionate de creosol
Martin, Robert,Gavard, Jean-Pierre,Delfly, Michel,Demerseman, Pierre,Tromelin, Anne
, p. 659 - 662 (2007/10/02)
The Fries rearrangement of creosol acetate and propionate yields meta acylphenols through meta ketoesters according to an intermolecular process.The acyl group undergoes a migration to the meta position, solely due to the combination of the electronic effects of the other substituents.A similar directing effect occurs in a transacylation reaction between a ketoester of creosol and the creosol itself.The two hitherto unknown propiophenones stemming from isocreosol are synthesized and described.
