91971-96-9Relevant academic research and scientific papers
Riminophenazine derivatives as potential antituberculosis agents: Synthesis, biological, and electrochemical evaluations
Bvumbi, Mpelegeng Victoria,van der Westhuyzen, Chris,Mmutlane, Edwin M.,Ngwane, Andile
, (2021/07/26)
A series of novel riminophenazine derivatives, having ionizable alkyl substituents at N-5 and a variety of substituents on the C-3 imino nitrogen, at C-8 and on the pendant aryl group, have been designed and synthesized. Preliminary investigations into th
Design, synthesis and biological evaluation of novel 7-alkylamino substituted benzo[ a[phenazin derivatives as dual topoisomerase I/II inhibitors
Yao, Bing-Lei,Mai, Yan-Wen,Chen, Shuo-Bin,Xie, Hua-Ting,Yao, Pei-Fen,Ou, Tian-Miao,Tan, Jia-Heng,Wang, Hong-Gen,Li, Ding,Huang, Shi-Liang,Gu, Lian-Quan,Huang, Zhi-Shu
, p. 540 - 553 (2015/01/30)
A novel series of benzo[a]phenazin derivatives bearing alkylamino side chains were designed, synthesized and evaluated for their topoisomerases inhibitory activity as well as cytotoxicity against four human cancer cell lines (HL-60, K-562, HeLa, and A549)
Parallel synthesis of a series of potentially brain penetrant aminoalkyl benzoimidazoles
Micco, Iolanda,Nencini, Arianna,Quinn, Joanna,Bothmann, Hendrick,Ghiron, Chiara,Padova, Alessandro,Papini, Silvia
, p. 2313 - 2328 (2008/09/21)
Alpha7 agonists were identified via GOLD (CCDC) docking in the putative agonist binding site of an alpha7 homology model and a series of aminoalkyl benzoimidazoles was synthesised to obtain potentially brain penetrant drugs. The array was prepared startin
