92016-66-5Relevant academic research and scientific papers
Functionalization of unprotected uracil derivatives using the halogen - Magnesium exchange
Kopp, Felix,Knoechel, Paul
, p. 1639 - 1641 (2008/02/02)
The reaction of commercially available 5-iodouracil with 2 equiv of MeMgCl in the presence of LiCl, followed by the addition of i-PrMgCl-LiCl, provides the corresponding trimagnesiated species, which reacts with various electrophiles to give selectively 5
Grignard and cerium reagents of pyrimidine derivatives
Shimura, Akihiko,Momotake, Atsuya,Togo, Hideo,Yokoyama, Masataka
, p. 495 - 499 (2007/10/03)
5-(Pyrimidinyl)magnesium and cerium chlorides were prepared via the halogen-metal exchange of 5-bromopyrimidine with ethylmagnesium chloride and a sequential treatment of butyl-lithium and cerium(III) chloride, respectively. In a similar way, 5-[2,4-di(te
