920313-46-8

Basic information

• Product Name: 5-Thiazolepropanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-
• Synonyms: 5-Thiazolepropanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-
• CAS NO: 920313-46-8
• Molecular Formula: C₁₁H₁₆N₂O₄S
• Molecular Weight: 272.32
• Mol File: 920313-46-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-Thiazolepropanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Thiazolepropanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-(920313-46-8)
• EPA Substance Registry System: 5-Thiazolepropanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-(920313-46-8)

Safety Data

• Hazardous Substances Data: 920313-46-8(Hazardous Substances Data)

Upstream product

• 1501-26-4 methyl 4-(chlorocarbonyl)butyrate 
• 6026-86-4 methyl 4-formylbutanoate 
• 883501-73-3 3-(2-Amino-thiazol-5-yl)-propionic acid methyl ester 

Downstream Products

• 936449-26-2 3-(2-Amino-thiazol-5-yl)-N-(3-fluoro-phenyl)-propionamide 

Relevant articles and documents

Thiazole Analogues and Uses Thereof

Compounds of formula (I) and salts and physiologically functional derivatives thereof, wherein R2 is attached at the 4- or 5-position of the thiazole ring and is hydrogen, alkyl, halogen, cyano, alkoxy, haloalkoxy, or alkylamino; X independently represents a divalent linkage group selected from S, O, NR4, SO, or SO2; R4 is hydrogen, alkyl, cycloalkyl, cycloalkylalkyl, or heterocyclyl; R1 is attached at the 4- or 5-position of the thiazole ring and independently represents a group of formula (II): ?wherein the dotted line represents a single or double bond; * indicates the point of attachment to the thiazole ring; and n is 1, 2, or 3. Also disclosed are pharmaceutical compositions comprising the above compounds and method of treatments for cancer and other diseases.