92039-20-8

Upstream product

• 260-94-6 acridine 
• 92-81-9 acridine 
• 3295-64-5 1,2,3,4-tetrahydroacridine 
• 123-91-1 1,4-dioxane 

Downstream Products

• 3295-64-5 1,2,3,4-tetrahydroacridine 
• 92-81-9 acridine 
• 1658-08-8 1,2,3,4,5,6,7,8-octahydroacridine 
• 1191071-91-6 (4aS,9aS)-1,2,3,4,4a,9,9a,10-octahydroacridine 
• 1201799-72-5 (4aR,9aR)-1,2,3,4,4a,9,9a,10-octahydroacridine 

Relevant academic research and scientific papers

Ruthenium nanoparticles supported on magnesium oxide: A versatile and recyclable dual-site catalyst for hydrogenation of mono- and poly-cyclic arenes, N-heteroaromatics, and S-heteroaromatics

The development of catalysts capable of promoting hydrogenation of aromatics while being resistant to poisoning by nitrogen- and sulfur-containing species is of much interest in connection with hydrotreating of fossil fuels. We report a catalyst composed of ruthenium nanoparticles supported on magnesia, designed to promote heterolytic hydrogen splitting and surface ionic hydrogenation pathways. The catalyst, prepared through a one-pot procedure, promotes the hydrogenation of mono- and poly-cyclic arenes, as well as N- and S-heteroaromatics representative of fossil fuels components. Of particular significance are the superior activity and wider substrate scope of the catalyst, in relation to other known supported noble metals, and the excellent recyclability and long catalyst lifetime. Based on our experimental data, a dual-site catalyst structure and an associated dual-pathway mechanism are proposed, which may have interesting implications for the development of new poison-tolerant noble metal catalytic systems.

The Effect of Hydrogen Sulfide on Acridine Hydrodenitrogenation on a Sulfided NiMo/Al2O3 Catalyst

The effect of hydrogen sulfide on acridine hydrodenitrogenation over a sulfided NiMo/Al2O3 catalyst at 280-380 deg C and 10.1 MPa total pressure was studied.The result showed that the presence of H2S depressed the total C-N hydrogenolysis at a low PH2S/PH2 ratio of 1.1-79x10-5, but that it rarely affected the C-N hydrogenolysis at a ratio above 0.003.

Selective Hydrogenation of 9-Aminoacridine over Supported Noble Metal Catalysts

The selective hydrogenation of 9-aminoacridine (1) into 1,2,3,4-tetrahydro-derivative (2) was searched using noble metal catalysts (Pd, Rh, Pt, and Ru) at around 80 deg C and 60 atm of H2.The Pd/Al2O3 catalyst was found most selective to produce 2 in a higher yield of 60 percent at a conversion of 97 percent.The hydrogenation pathway of 1 is discussed in comparison with that of acridine.

Kinetics and Stereochemistry in the Catalytic Hydrogenation of Acridine

Hydogenation of acridine (1) using a commercial Pd-Al2O3 catalyst was kinetically and stereochemically studied under variable conditions.A consecutive pathway, (1) -> 9,10-dihydroacridine (2) -> 1,2,3,4,4a,9,9a,10-octahydroacridine (5), which competes with hydrogenative isomerisation of (2) to 1,2,3,4,5,6,7,8-octahydroacridine (4) via 1,2,3,4-tetrahydroacridine (3) or (5) was suggested from the observed product distributions over the time course of the reactions and their kinetic simulation.Thus, selectivity for the hydrogenated products is found to be controlled by either kinetics or thermodymanics according to the reaction conditions.Thermodynamic stabilities of the products are discussed based on quantum chemical (MNDO) and molecular mechenics (MM2) calculations to rationalize the reaction scheme.The stereoisomers of (5) and perhydroacridine (6) were identified and quantified by detail analyses using g.c.-i.r. and (13)C n.m.r.The stereoselectivity is governed by the preference in adsorption of the intermediates on the catalyst surface at a lower reaction temperature (150 deg C); however, a higher temperature (250 deg C) produces the thermodynamically stable products through equilibrium control.