920502-55-2

Upstream product

• 920502-53-0 methyl (4R)-4-[(phenylthio)-acetoxy]-7-tert-butyldiphenylsilyloxy-hepten-2(E)-oate 
• 920502-52-9 (2S,3R)-1,2-dihydro-6-tert-butyldiphenylsilyloxy-hexan-3-yl 2-(phenylthio)acetate 
• 127379-30-0 (2S,3S)-(3-(3-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)propyl)-2-oxiranyl)methan-1-ol 

Downstream Products

• 920502-60-9 (3S,4R,5R)-5-(2-hydroxy-ethyl)-3-phenylthio-5-(3-tert-butyldiphenylsilyloxy)propyl-dihydrofuran-2-one 
• 920502-61-0 (3S,4R,5R)-4-allyl-3-phenylthio-5-(3-tert-butyldiphenylsilyloxy)propyl-dihydrofuran-2-one 
• 920502-64-3 (3S,4R,5R)-4-allyl-5-(3-hydroxypropyl)-3-phenylthio-dihydrofuran-2-one 
• 920502-65-4 (3S,4R,5R)-4-allyl-5-(3-butenyl)-3-phenylthio-dihydrofuran-2-one 
• 920502-59-6 (2R,3R,4S)-[5-oxo-4-(phenylthio)-2-(3-tert-butyldiphenylsilyloxy)propyl-tetrahydrofuran-3-yl]acetic acid 

Relevant academic research and scientific papers

γ-Lactones as templates in ring-closing metathesis: Enantioselective synthesis of medium sized carbocycles fused to butyrolactones

A methodology for accessing enantiomerically enriched carbocyclic systems fused to γ-lactones is described. Key steps are the stereoselective synthesis of highly substituted γ-lactones and ring-closing metathesis of the suitable ramifications. The process permits the choice of stereochemistry, regioselectivity and ring size of the fused compounds.