92074-46-9Relevant academic research and scientific papers
Organophosphorus Compounds. XX. Approaches to the Synthesis of 2,3-Dihydro-1H-1.2-benzazaphospholes Involving C-C and C-P Ring Closure
Collins, David J.,Drygala, Peter F.,Swan, John M.
, p. 1009 - 1021 (2007/10/02)
Reaction of chloromethylphosphonic dichloride (9) with N-methylaniline gave N,N'-dimethyl-N,N'-diphenylchloromethylphosphonodiamide (10) which upon treatment with aluminium chloride underwent intramolecular Friedel-Crafts alkylation to afford 1-methyl-2-(N'-methyl-N'-phenylamino)-2,3-dihydro-1H-1,2-benzazaphosphole 2-oxide (13a).Similarly, N-methyl-N-phenyl(chloromethyl)phenylphosphinamide (15) was cyclized to give 1-methyl-2-phenyl-2,3-dihydro-1H-1,2-benzazaphosphole 2-oxide (13b). Some unsuccessful approaches to this heterocyclic ring system are also reported.
