920796-72-1Relevant academic research and scientific papers
Scandium(III) triflate mediated intramolecular ring expansion of aziridines: A direct access to 4-aryltetrahydroisoquinolines
Satyanarayana, Tummanapalli,Muthuraman, Parthasarathy,Vangapandu, Dhanunjaya Naidu,Majumder, Supriyo
, p. 6787 - 6790 (2015/01/08)
A novel, high yielding facile synthesis of 4-substituted tetrahydroisoquinolines has been developed by employing scandium(III) triflate mediated intramolecular ring expansion of aziridines. The meta-substituted electron-donating group on the benzene ring facilitates trapping of an in situ generated benzyl carbenium ion cation leading to the formation of tetrahydroisoquinolines.
INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF
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Page/Page column 81, (2008/06/13)
The present invention relates to a production method of an optically active morpholine compound represented by the formula 10, which includes the following steps: wherein each symbol is as defined in the specification. The present invention also relates t
