920974-72-7

Upstream product

• 920974-55-6 Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-{2-chloro-6-[(R)-(tetrahydro-furan-3-yl)amino]-purin-9-yl}-tetrahydro-furan-3-yl ester 
• 3056-18-6 (2R,3R,4R,5R)-4-(acetyloxy)-2-[(acetyloxy)methyl]-5-(2,6-dichloro-9H-purin-9-yl)tetrahydro-3-furanyl acetate 
• 920974-66-9 {(3aR,4R,6R,6aR)-2,2-Dimethyl-6-[6-[(R)-(tetrahydro-furan-3-yl)amino]-2-(4-p-tolyl-pyrazol-1-yl)-purin-9-yl]-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl}-methanol 
• 920974-61-4 (2R,3S,4R,5R)-2-Hydroxymethyl-5-[6-[(R)-(tetrahydro-furan-3-yl)amino]-2-(4-p-tolyl-pyrazol-1-yl)-purin-9-yl]-tetrahydro-furan-3,4-diol 
• 920974-69-2 (3aS,4S,6R,6aR)-2,2-Dimethyl-6-[6-[(R)-(tetrahydro-furan-3-yl)amino]-2-(4-p-tolyl-pyrazol-1-yl)-purin-9-yl]-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid 
• 557-66-4 ethanamine hydrochloride 
• 920974-56-7 (2R,3R,4S,5R)-2-{2-Hydrazino-6-[(R)-(tetrahydro-furan-3-yl)amino]-purin-9-yl}-5-hydroxymethyl-tetrahydro-furan-3,4-diol 

Relevant academic research and scientific papers

N6-Cycloalkyl-2-substituted adenosine derivatives as selective, high affinity adenosine A1 receptor agonists

A series of new selective, high affinity A1-AdoR agonists is reported. Compound 23 that incorporated a carboxylic acid functionality in the 4-position of the pyrazole ring displayed KiL value of 1 nM for the A1-AdoR and >5