92148-47-5Relevant academic research and scientific papers
Highly Chemoselective gem-Difluoropropargylation of Aliphatic Alcohols
Okamura, Toshitaka,Egoshi, Syusuke,Dodo, Kosuke,Sodeoka, Mikiko,Iwabuchi, Yoshiharu,Kanoh, Naoki
supporting information, p. 16002 - 16006 (2019/11/19)
Despite the potential of α-fluoroethers in medicinal chemistry, their synthetic methods, especially etherification of aliphatic alcohols, have been limited. Herein, we developed two- and three-step gem-difluoropropargylation of aliphatic alcohols includin
2-PYRIDYL CARBOXAMIDE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS
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Paragraph 00313, (2013/04/24)
The invention provides certain 2-pyridyl carboxamide-containing compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein A and B are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase.
An efficient and selective deprotection of tetrahydropyranyl ethers by CeCl3.7H2O
Reddy,Neelakantan,Iyengar
, p. 4107 - 4111 (2007/10/03)
Treatment of tetrahydropyranyl ethers with cerium (III) chloride heptahydrate in methanol provides a simple, convenient and selective method for detetrahydropyranylation, and the parent alcohols are obtained in high yields.
