33900-24-2

Basic information

• Product Name: L-Methionine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester
• Synonyms: BOC-Met-OMe;methyl N-(tert-butoxycarbonyl)methioninate;N-tert-butyloxucarbonyl-L-methionine methyl ester;N-(tert-butoxycarbonyl)-L-methionine methyl ester;N-tert-butyloxycarbonylmethionine methyl ester
• CAS NO: 33900-24-2
• Molecular Formula: C11H21NO4S
• Molecular Weight: 263.358
• Mol File: 33900-24-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: L-Methionine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Methionine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester(33900-24-2)
• EPA Substance Registry System: L-Methionine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester(33900-24-2)

Safety Data

• Hazardous Substances Data: 33900-24-2(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 100-36-7 N,N-diethylethylenediamine 
• 395647-22-0 N-{3-[(N,N-dimethylaminophenyl)-4'-diazenyl]benzoyl}-N-tert-butyloxycarbonylmethionine methyl ester 

Downstream Products

• 10332-17-9 DL-methionine methyl ester 
• 92148-47-5 tert-butyl [1-hydroxy-4-(methylsulfanyl)butan-2-yl]carbamate 
• 49759-74-2 N-tert-butoxycarbonyl-L-methionine hydrazide 
• 95656-85-2 tert-butyl (3-(methylthio)propyl)carbamate 
• 76220-79-6 (S)-tert-butyl 2-(1-tosyloxy-4-methylthio)butylcarbamate 
• 120369-51-9 (S)-tert-butyl 1-(benzylamino)-4-(methylthio)-1-oxobutan-2-ylcarbamate 
• 66880-59-9 (2S)-methyl2-(2-(tert-butoxycarbonylamino)-4-(methylthio)butanamido)-4-methylpentanoate 
• 106847-79-4 Boc-Met-Leu-Phe-NH₂ 
• 56762-93-7 methyl (S)-2-(benzyloxycarbonylamino)-4-methylmercaptobutanoate 
• 89985-86-4 (R)-2-(N-tert-butoxycarbonylamino)-3-buten-1-ol 

Relevant articles and documents

Development of a temporary marker for peptides

3-[(N,N-Dimethylaminophenyl)-4′-diazenyl]benzoic acid was coupled with several amino acid esters and the product acylated further with Boc. The material thus obtained was then submitted to cleavage by electrolysis and nucleophilic attack in order to evaluate the possibility of using this chromophore as a temporary marker.

The synthesis of di(hydroxyalkyl) substituted bicyclic guanidines

The synthesis of the enantiomerically pure bicyclic guanidines 3a and 3b is described.The convergent strategy is based on methodology developed by Schmidtchen.The therefore required amine components 6 and 9 obtained from methionine and L-glutamic acid, respectively.