92151-21-8

Upstream product

• 15164-44-0 p-(iodophenyl)carboxaldehyde 
• 849695-11-0 1-benzoyl-2-(4-iodobenzoyl)hydrazine 
• 613-94-5 benzoic acid hydrazide 
• 51934-41-9 4-iodobenzoic acid ethyl ester 
• 39115-95-2 4-iodobenzohydrazide 
• 65-85-0 benzoic acid 
• 619-44-3 methyl 4-iodobenzoate 

Downstream Products

• 957045-51-1 2-phenyl-5-[4-(phenylethynyl)phenyl]-1,3,4-oxadiazole 
• 637771-71-2 2-phenyl-5-(4-ethynylphenyl)-[1,3,4]oxadiazole 
• 1618094-92-0 N-hydroxy-3-(4-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl)acrylamide 
• 35955-59-0 C₁₇H₁₂N₂O₃ 
• 1618094-44-2 C₂₁H₂₀N₂O₃ 
• 1215232-06-6 3-phenyl-9-[4-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl]-9H-carbazole 

Relevant academic research and scientific papers

1,3,4-Oxadiazole-containing histone deacetylase inhibitors: Anticancer activities in cancer cells

We describe 1,3,4-oxadiazole-containing hydroxamates (2) and 2-aminoanilides (3) as histone deacetylase inhibitors. Among them, 2t, 2x, and 3i were the most potent and selective against HDAC1. In U937 leukemia cells, 2t was more potent than SAHA in inducing apoptosis, and 3i displayed cell differentiation with a potency similar to MS-275. In several acute myeloid leukemia (AML) cell lines, as well as in U937 cells in combination with doxorubicin, 3i showed higher antiproliferative effects than SAHA.

Microwave-assisted one-step synthesis of 2,5-disubstituted-1,3,4- oxadiazoles using 1,4- bis(triphenylphosphonium)-2-butene peroxodisulfate

A series of 1,3,4-oxadiazoles were efficiently synthesized from the cyclization-oxidation reaction of acyl hydrazones by using 1,4- bis(triphenylphosphonium)-2-butene peroxodisulfate as an oxidant in solvent-free medium under microwave irradiation.

17O NMR studies of substituted 1,3,4-oxadiazoles

Three series of substituted 1,3,4-oxadiazoles were studied by 17O NMR spectroscopy. Chemical shifts values were correlated with empirical Hammett parameters as well as calculated bond lengths and chemical shielding values.

A novel, one-pot synthesis of 2,5-disubstituted-1,3,4-oxadiazoles using 1,4-bis(Triphenylphosphonium)-2-butene peroxodisulfate

An efficient and convenient synthesis of 1,3,4-oxadiazoles from aromatic aldehydes, acyl hydrazide, and 1,4- bis(triphenylphosphonium)-2-butene peroxodisulfate is reported. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.

Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same

Disclosed is a novel organic semiconductor material which has a twisted quaterphenylene skeleton as a central unit and simultaneously possesses a skeleton having an electron-transporting property and a skeleton having a hole-transporting property at the t

Microwave assisted syntheses of 2,5-disubstituted 1,3,4-oxadiazoles

2,5-Di-substituted 1,3,4-oxadiazoles have been synthesized from the oxidation of 1-aroyl-2-arylidene hydrazines with potassium permanganate on the surface of solid mineral support as well as in the mixture of acetone and water under microwave irradiation. 2,5-Disubstituted 1,3,4-oxadiazoles have been synthesized by oxidation of 1-aroyl-2-arylidene hydrazines with potassium permanganate on the surface of a solid mineral support as well as in mixtures of acetone and water under microwave irradiation.