92161-65-4

Basic information

• Product Name: methyl 2-(4-chloro-2-nitrophenylthio)benzoate
• Synonyms: methyl 2-(4-chloro-2-nitrophenylthio)benzoate;2-[(4-chloro-2-nitrophenyl)thio]benzoic acid methyl ester;2-[(4-chloro-2-nitro-phenyl)thio]benzoic acid methyl ester;methyl 2-(4-chloro-2-nitrophenyl)sulfanylbenzoate;methyl 2-(4-chloro-2-nitro-phenyl)sulfanylbenzoate;MFCD08582838
• CAS NO: 92161-65-4
• Molecular Formula: C₁₄H₁₀ClNO₄S
• Molecular Weight: 323.76
• Mol File: 92161-65-4.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: methyl 2-(4-chloro-2-nitrophenylthio)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(4-chloro-2-nitrophenylthio)benzoate(92161-65-4)
• EPA Substance Registry System: methyl 2-(4-chloro-2-nitrophenylthio)benzoate(92161-65-4)

Safety Data

• Hazardous Substances Data: 92161-65-4(Hazardous Substances Data)

Usage

Uses

Methyl 2-((4-chloro-2-nitrophenyl)thio)benzoate is a useful intermediate for organic synthesis.

Upstream product

• 345-18-6 2-fluoro-5-chloronitrobenzene 
• 4892-02-8 Methyl thiosalicylate 
• 60-29-7 diethyl ether 
• 17999-25-6 methyl thiosalicylate 
• 89-61-2 2,5-dichloronitrobenzene 
• 700-37-8 4-chloro-2-fluoro-nitrobenzene 

Downstream Products

• 126395-03-7 2-(4-chloro-2-nitrophenylsulfanyl)benzoic acid 
• 1451261-79-2 2-({2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chlorophenyl}sulfanyl)benzoic acid 
• 1071718-24-5 methyl 2-((2-amino-4-chlorophenyl)thio)benzoate hydrochloride salt 
• 3158-80-3 8-chloro-10H-dibenzo[b,f][1,4]thiazepin-11-one 
• 93535-13-8 2-(2-amino-4-chloro-phenylsulfanyl)-benzoic acid methyl ester 
• 167996-98-7 2-(2-amino-4-chlorophenylsulfanyl)benzoic acid 

Relevant articles and documents

BENZOFURAN-2-SULFONAMIDES DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS

The present invention relates to novel benzofuran-2-sulfonamide derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of chemokine receptors.

IRON CATALYZED CROSS-COUPLING REACTIONS OF IMIDOYL DERIVATIVES

Disclosed is a process for preparing a compound of formula A - N=C(D)(B), from a compound of formula A-N=C(E)(B) and a compound of formula D-M using an iron catalyst, where the process has is represented by Equation (I).

Iron-catalyzed cross-coupling of imidoyl chlorides with Grignard reagents

A general, high yielding rapid iron-catalyzed cross-coupling reaction between Grignard reagents and imidoyl chlorides is described. These reactions are typically completed within 5 min, resulting in high yields of 71-96% using 5% iron catalyst in a THF-NM