921630-35-5

Upstream product

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• 7499-06-1 5-chloro-2-methylbenzoic acid 
• 1229246-27-8 1,1-dimethylethyl cyclopropyl({2-methyl-5-[(1E)-3-(methyloxy)-1-propen-1-yl]phenyl}methyl)carbamate 
• 1229246-29-0 1,1-dimethylethyl [(5-chloro-2-methylphenyl)methyl]cyclopropylcarbamate 
• 1229246-31-4 5-chloro-N-cyclopropyl-2-methylbenzamide 
• 1229246-30-3 N-[(5-chloro-2-methylphenyl)methyl]cyclopropanamine 

Relevant academic research and scientific papers

3, 4 - SUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS

The present invention relates to 3,4-substituted piperidinyl - based renin inhibitor compounds bearing at 4-position lsoqumolone and having the Formula (I) : The invention further relates to pharmaceutical compositions containing said compounds, as well a

3, 4 - SUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS

The present invention relates to 3,4-substituted piperidinyl-based renin inhibitor compounds bearing at 4-position oxopyridine and having the formula (I). The invention further relates to pharmaceutical compositions containing said compounds, as well as their use in treating cardiovascular events and renal insufficiency.

RENIN INHIBITORS

The present invention relates to novel renin inhibitors of the general Formula (I), and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds. These novel renin inhibitors are used in treating cardiovascular events and renal insufficiency.