92181-58-3

Upstream product

• 14096-51-6 dichloro(ethylenediamine)platinum(II) 
• 68558-86-1 thallium(I) pentafluorobenzoate 
• 363-72-4 Pentafluorobenzene 
• 23858-10-8 cis-(ethylenediamine)diiodoplatinum(II) 
• 110-86-1 pyridine 
• 135389-34-3 bis-iodo{N-(2,3,5,6-tetrafluorophenyl)ethane-1,2-diamine}platinum(II) 

Downstream Products

• 1404372-33-3 cis,trans,cis-[N,N'-bis(2,3,5,6-tetrafluorophenyl)ethane-1,2-diaminato]dichlorodipyridineplatinum(IV) 
• 1404372-35-5 cis,trans,cis-[N,N?'-bis(2,3,5,6-tetrafluorophenyl)ethane-1,2-diaminato]dihydroxydipyridineplatinum(IV) 
• 1404372-36-6 cis,trans,cis-[N,N?'-bis(2,3,5,6-tetrafluorophenyl)ethane-1,2-diaminato]chlorohydroxydipyridineplatinum(IV) 

Relevant academic research and scientific papers

Organoamidometallics - VI. A new synthetic route to [N,N′-bis(polyfluorophenyl)ethane-1,2-diaminato(2-)]dipyridineplatinum(II) complexes and the preparation of [N-phenyl-N′-(polyfluorophenyl)ethane-1,2-diaminato(2-)] dipyridineplatinum(II) complexes

Reaction of [Pt(en)Cl2] (en = ethane-1.2-diamine) with thallium(I) carbonate (or in some cases K2CO3) and a polyfluorobenzene in hot pyridine (py) or 3-methylpyridine (tmpy) yields the [N,N′-bis (polyfluorophenyl)ethane-1,2-diaminato(2-)]platinum(II) complexes, [Pt{N(R)CH2}2L2] (L = py, R = p-HC6F4, C6F5, p-BrC6F4, p-IC6F4, p-MeC6F4, p-C6F5C6F4, 2,3,5-F3C6H2, p-O(H)CC6F4, p-MeOC6F4; L = tmpy, R = p-HC6F4). Yields were markedly greater with the use of Tl2CO3 than reported for reactions of [Pt(en)Cl2] with thallium(I) polyfluorobenzoates. A new class of platinum(II) amides, namely [N-(phenyl)-N′-(polyfluorophenyI)ethane-1,2-diaminato(2-)]platinum(II) complexes, [Pt{N(Ph)CH2CH2N(R)}L2] (L = py, R = p-HC6F4, C6F5, p-MeC6F4, p-ClC6F4, P-BrC6F4; L = 4-methylpyridine, R = P-HC6F4), has been prepared by reaction of [Pt(PhNHCH2CH2NH2)I2] with Tl2CO3 or a thallium(I) polyfluorobenzoate and a polyfluoroaromatic compound in pyridine or 4-methylpyridine. The complexes where R = p-MeC6F4, p-ClC6F4, p-BrC6F4 could be prepared only with Tl2CO3, which also provided cleaner products where both routes were used. The crystal structure of [Pt{N(Ph)CH2CH2N(p-MeC6F4)} (py)2] has been determined and shows a slightly distorted square planar coordination for platinum, with two amide and two cis pyridine nitrogen donors.

Organoamidometallics. I Syntheses of platinum(II) Complexes by Decarboxylation

Reaction of PtCl2(en) (en = ethane-1,2-diamine) with thallous pentafluorobenzoate in hot pyridine (py) or 4-methylpyridine (mepy) yields the platinum(II) complexes, Pt2(py)2 (1a) and Pt2(mepy)2 (1b).The route to (1a) is considered to involve formation of (O2CC6F5)2 (2), decarboxylation of (2) into Pt(NHCH2)2(py)2 (1c) and pentafluorobenzene and nucleophilic attack of (1c) on C6F5H.Complex (1a) has also been prepared by decarboxylation of (2), reaction of PtI2(en) and TlO2CC6F5, and reaction of PtCl2(en), C6F5H, and TlO2CC6F4H-p in boiling pyridine.From reaction of PtCl2(en), TlO2CC6F4H-p, and the appropriate polyfluorobenzene (RF) in boiling pyridine or 4-methylpyridine, the organoamidoplatinum compounds Pt(NRCH2)2L2 (R = C6F5, p-MeC6F4, p-ClC6F4, p-BrC6F4, p-IC6F4, 2,3,5-F3C6H2, or p-C6F5C6F4, L = py and R = C6F5, L = mepy) have been prepared.Analogous reactions of PtCl2(pn) (pn = propane-1,3-diamine) give the complexes (R = C6F5 or p-HC6F4).Spectroscopic evidence for the structures is discussed.The polyfluorophenyl groups confer stability to water on ethane-1,2-diaminato(2-)platinum(II) complexes, and this is attributable to delocalization of non-bonded lone pairs from the amido nitrogens into the polyfluorophenyl rings.