92184-45-7 Usage
Uses
Used in Medicinal Chemistry:
2,4-diamino-N-(3-bromophenyl)quinazoline-6-sulfonamide is used as a compound of interest in medicinal chemistry for its potential biological activity. The presence of the quinazoline ring and the sulfonamide group, along with the bromophenyl and amino groups, suggests that it may interact with biological targets, offering opportunities for the development of new drugs.
Used in Drug Discovery:
In the pharmaceutical industry, 2,4-diamino-N-(3-bromophenyl)quinazoline-6-sulfonamide is used as a starting material or a scaffold in drug discovery processes. Its unique structure may allow for the design of new therapeutic agents that can target specific biological pathways or receptors, contributing to the advancement of medicine.
Used in Research and Development:
2,4-diamino-N-(3-bromophenyl)quinazoline-6-sulfonamide serves as a subject of research and development in academic and industrial laboratories. Scientists are likely to investigate its chemical properties, potential interactions with biological systems, and its efficacy and safety in various disease models to determine its suitability as a therapeutic agent.
Check Digit Verification of cas no
The CAS Registry Mumber 92184-45-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,1,8 and 4 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 92184-45:
(7*9)+(6*2)+(5*1)+(4*8)+(3*4)+(2*4)+(1*5)=137
137 % 10 = 7
So 92184-45-7 is a valid CAS Registry Number.
92184-45-7Relevant academic research and scientific papers
Folate antagonists. 22. Antimalarial and antibacterial effects of 2,4-diamino-6-quinazolinesulfonamides
Elslager,Colbry,Davoll,Hutt,Johnson,Werbel
, p. 1740 - 1743 (2007/10/02)
The synthesis and antimalarial activity of a series of 2,4-diamino-6-quinazolinesulfonamides is described. Chlorosulfonation of 2,4-quinazolinediamine affords the 6-sulfonyl chloride, which upon treatment with the appropriate amine produces the desired products. Alternatively the sulfonyl chloride could be introduced by diazotization of the corresponding amine followed by treatment with SO2 in the presence of CuCl2. Although substantial antimalarial activity was demonstrated for several members of this class, studies were discontinued in light of the potency of related series.
