92192-94-4

Usage

Uses

Used in Rubber Industry:
1-Benzhydryl-2-thiourea is used as a rubber accelerator for enhancing the vulcanization process. It improves the overall properties of rubber products, such as tensile strength, elasticity, and resistance to wear and tear.
Used in Agriculture:
1-Benzhydryl-2-thiourea is used as a fungicide to control various fungal diseases in crops. It helps protect plants from infections and ensures a healthy and productive agricultural yield.
However, the use of 1-Benzhydryl-2-thiourea has raised concerns about its potential environmental and health impacts. It is crucial to handle and dispose of it properly to minimize these risks and ensure the safety of both the environment and human health.

InChI:InChI=1/C14H14N2S/c15-14(17)16-13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,13H,(H3,15,16,17)

Upstream product

• 3550-21-8 diphenylmethyl isothiocyanate 
• 1147550-11-5 ammonium thiocyanate 
• 776-74-9 Bromodiphenylmethane 
• 91-00-9 Benzhydrylamine 
• 5267-34-5 aminodiphenylmethane hydrochloride 

Downstream Products

• 109809-51-0 2-benzhydrylamino-5-methyl-thiazol-4-one 
• 70841-58-6 N-benzhydryl-S-methyl-isothiourea 
• 138460-24-9 C₁₄H₁₄N₂O₃S 
• 7152-82-1 1-Benzhydryl-2-methyl-isothiourea; hydriodide 
• 102181-42-0 2-benzhydrylamino-5-butyl-thiazol-4-one 
• 102026-47-1 benzhydryl-(4-methyl-thiazol-2-yl)-amine 
• 101350-53-2 2-benzhydrylamino-thiazol-4-one 
• 25221-33-4 2-benzhydrylamino-5,5-diphenyl-thiazol-4-one 
• 68696-30-0 N-benzhydryl-N',S-dimethyl-isothiourea; hydriodide 
• 65069-97-8 N-benzhydryl-morpholine-4-carboximidic acid amide 
• 65069-99-0 N-Benzhydryl-pyrrolidine-1-carboxamidine; hydriodide 
• 138460-21-6 (N'-Benzhydryl-guanidino)-acetic acid 

Relevant academic research and scientific papers

Synthesis of thiophene-2-carboxamidines containing 2-aminothiazoles and their biological evaluation as urokinase inhibitors

The serine protease urokinase (uPa) has been implicated in the progression of both breast and prostate cancer. Utilizing structure based design, the synthesis of a series of substituted 4-[2-amino-1,3-thiazolyl]-thiophene-2-carboxamidines is described. Further optimization of this series by substitution of the terminal amine yielded urokinase inhibitors with excellent activities.

Tricyclic compounds, their production and use

A compound of the formula: wherein R1 is H or a substituent; m is 1-3; Ar is an aromatic group which may be substituted; X is a bond or a divalent straight-chain group having 1-6 atoms which may be substituted; Y is —S—, —O—, or —N(R2— (R2 is H or a substituent group), Z is —N= or —C(R3)= (R3 is H or a hydrocarbon group), ring A is a benzene ring; ring B is a 5- to 7-membered ring which may be substituted, or a salt thereof is useful for eliciting a prostaglandin I2 receptor agonistic effect.

N,N'-disubstituted guanidine high-potency sweeteners

The role and function of the aryl group in the highly potent trisubstituted guanidine sweeteners 7a-d was investigated. Four disubstituted guanidines, lacking the aryl group, were prepared. These guanidines contain a hydrophobic substituent on one nitroge