92199-07-0

Basic information

• Product Name: 1H-Indole, 2,3-dihydro-7-phenyl-
• Synonyms: 7-Phenyl-2,3-dihydro-indol
• CAS NO: 92199-07-0
• Molecular Formula: C14H13N
• Molecular Weight: 195.264
• Mol File: 92199-07-0.mol

Chemical Properties

• Boiling Point: 369.6±32.0 °C(Predicted)
• Density: 1.085±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1H-Indole, 2,3-dihydro-7-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 2,3-dihydro-7-phenyl-(92199-07-0)
• EPA Substance Registry System: 1H-Indole, 2,3-dihydro-7-phenyl-(92199-07-0)

Safety Data

• Hazardous Substances Data: 92199-07-0(Hazardous Substances Data)

Usage

Chemical class

Indole class of organic compounds

Structure

Bicyclic structure consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring

Usage

Building block in the synthesis of pharmaceuticals, agrochemicals, and organic compounds

Biological activities

Antiviral, anticancer, and anti-inflammatory properties

Aromatic properties

Used in the production of dyes, fragrances, and flavors

Upstream product

• 7633-56-9 N-aminoindoline 
• 71-43-2 benzene 
• 1863-21-4 7-(phenyl)-1H-indole 

Downstream Products

• 1254363-77-3 1-((4-methoxyphenyl)sulfonyl)-7-phenylindoline 
• 1863-21-4 7-(phenyl)-1H-indole 

Relevant articles and documents

Pyridazine N-Oxides as Precursors of Metallocarbenes: Rhodium-Catalyzed Transannulation with Pyrroles

Pyridazine N-oxides are used for the first time as precursors of metallocarbenes. These nitrogen-rich heterocycles led to the discovery of a novel acceptor and donor-acceptor enalcarbenoids. The synthetic utility of these metallocarbenes was demonstrated in the rhodium-catalyzed denitrogenative transannulation of pyridazine N-oxides with pyrroles to the valuable alkyl, 7-aryl, and 7-styryl indoles. The transannulation strategy was applied to the synthesis of a potent anticancer agent.

Phenylaminopropanol derivatives and methods of their use

The present invention is directed to phenylaminopropanol derivatives of formulae I, II, and III: [image] or a pharmaceutically acceptable salt thereof, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromyalgia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, schizophrenia, and combinations thereof.

A TRIFLUOROMETHANESULFONIC ACID-CATALYZED REACTION OF ARYLHYDRAZINES WITH BENZENE

Arylhydrazines reacted with benzene in the presence of trifluoromethanesulfonic acid (TFSA) to give aminobiphenyls.This is a general method for the synthesis of aminobiphenyls.