92248-19-6

Upstream product

• 24139-56-8 ethyl 2-cyano-5-phenyl-2,4-pentadienoate 
• 41109-95-9 (2E,4E)-2-cyano-5-phenyl-2,4-pentadienoic acid ethyl ester 

Relevant academic research and scientific papers

Catalyst-free chemoselective reduction of the carbon-carbon double bond in conjugated alkenes with Hantzsch esters in water

A simple, efficient and green protocol for chemoselective reduction of carbon-carbon double bond in conjugated alkenes with Hantzsch esters is described. Without any additional catalysts, a series of conjugated alkenes with strong electron-withdrawing groups were reduced in water with excellent yield. Functional groups such as nitrile, ester, nitro, fluoro, chloro, bromo, furanyl and benzyl are all tolerated by the reaction conditions employed. The Royal Society of Chemistry.

3-Butyl-1-methylimidazolinium borohydride ([bmim][BH4])-a novel reducing agent for the selective reduction of carbon-carbon double bonds in activated conjugated alkenes

A novel ionic reducing reagent, 3-butyl-1-methylimidazolium borohydride ([bmim][BH4]), was synthesized and successfully used for the selective reduction of carbon-carbon double bonds in conjugated alkenes as well as the α,β-carbon-carbon double bonds in highly activated α,β,γ,δ-unsaturated alkenes. The reagent can be regenerated and reused several times without losing its activity.

A facile and chemoselective conjugate reduction using polymethylhydrosiloxane (PMHS) and catalytic B(C6F5) 3

A highly chemoselective conjugate reduction of electron-deficient Michael acceptors, including Α, β-unsaturated ketones, carboxylic esters, nitriles and nitro compounds with PMHS in the presence of catalytic B(C 6F5)3 was investigated. When attempts were made to improve the yields by increasing the amount of catalyst, the result was a complex mixture of saturated and unsaturated compounds, with partial reduction of the ketone moiety to the methylene functionality. PMHS along with a catalytic amount of B(C6F5)3 was found to be a unique reagent system for the conjugate reduction of Michael acceptors.

Remarkably selective reduction of the α,β-carbon-carbon double bond in highly activated α,β,γ,δ-unsaturated alkenes by the InCl3-NaBH4 reagent system

A combination of sodium borohydride and a catalytic amount of indium(III) chloride in acetonitrile reduces exclusively the α,β-carbon-carbon double bond in α,β,γ,δ-unsaturated diaryl ketones, dicarboxylic ester, cyano-ester, and dicyano compounds.