92248-33-4Relevant academic research and scientific papers
Gold-catalyzed substitution reaction with ortho-alkynylbenzoic acid alkyl ester as an efficient alkylating agent
Aikawa, Haruo,Tago, Sakie,Umetsu, Kazuteru,Haginiwa, Naomichi,Asao, Naoki
experimental part, p. 1774 - 1784 (2009/06/20)
ortho-Alkynylbenzoic acid alkyl esters behave as alkylating agents in combination with gold catalysts. The reaction with alcohols occurs smoothly in the presence of catalytic amounts of Ph3PAuCl and AgOTf under mild conditions to produce the corresponding ether products in high yields. The protocol is also useful for Friedel-Crafts alkylation and N-alkylation of sulfonamides. The reaction likely proceeds through the gold-induced in situ construction of leaving groups and subsequent nucleophilic attack of nucleophiles, such as alcohols, aromatic compounds, and sulfonamides.
A useful Pd-catalyzed Negishi coupling approach to benzylic sulfonamide derivatives
Zhou, Gang,Ting, Pauline,Aslanian, Robert,Piwinski, John J.
experimental part, p. 2517 - 2520 (2009/05/26)
(Chemical Equation Presented) A mild catalytic system to access diversely functionalized benzylic sulfonamides has been developed. Palladium-catalyzed α-arylation by Negishi cross-coupling of sulfonamide-stabilized anions and a wide range of aryl iodides, bromides, and triflates constitutes a practical strategy for the synthesis of various benzylic sulfonamides.
Linker binding carriers for organic synthesis, their production and use
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Page column 37-39, (2010/02/05)
The present invention provides a linker binding carrier for organic synthesis represented by the formula: ?—Z—W—(SO2X)m wherein ? is a carrier, X is a leaving group, Y is a bond or spacer, Z is a bivalent group, when Z is a bivalent electron at
