922527-71-7Relevant academic research and scientific papers
Studies towards lipid A: a synthetic strategy for the enantioselective preparation of 3-hydroxy fatty acids
Guaragna, Annalisa,Nisco, Mauro De,Pedatella, Silvana,Palumbo, Giovanni
, p. 2839 - 2841 (2006)
A short and efficient enantioselective synthesis of (R)-3-hydroxydodecanoic acid is described, involving a Sharpless asymmetric dihydroxylation to produce the required (R)-stereochemistry.
Total synthesis of fellutamides, lipopeptide proteasome inhibitors. More sustainable peptide bond formation
Pirrung, Michael C.,Zhang, Fa,Ambadi, Sudhakar,Gangadhara Rao
, p. 8367 - 8375 (2016/09/09)
Solution-phase syntheses of three bioactive natural products of mixed polypeptide-polyketide biogenesis, fellutamides A, B, and C, have been achieved. Three peptide bonds are generated without the use of coupling reagents in each synthesis of the fellutamides, which act against proteasomes.
