922529-76-8Relevant academic research and scientific papers
Formation of bi-aryls via a domino palladium catalysis
Krishna,Gopi Krishna Reddy,Satyanarayana
, p. 861 - 864 (2015/03/05)
Synthesis of bi-aryls via a domino Pd-catalyzed reaction of 1-(2-bromophenyl)-2-methylpropan-1-ones/(2-bromophenyl)(cyclohexyl)methanones is presented. The mechanism of the reaction is believed to proceed through a five membered palladacycle that combines with a second molecule of halo-arene to yield the bi-aryls. This method is quite successful to deliver highly sterically crowded bi-aryls with dense functionalities on the aromatic rings.
Formation of bi-aryls via a domino palladium catalysis
Krishna,Reddy, A. Gopi Krishna,Satyanarayana
, p. 861 - 864 (2014/02/14)
Synthesis of bi-aryls via a domino Pd-catalyzed reaction of 1-(2-bromophenyl)-2-methylpropan-1-ones/(2-bromophenyl)(cyclohexyl)methanones is presented. The mechanism of the reaction is believed to proceed through a five membered palladacycle that combines with a second molecule of halo-arene to yield the bi-aryls. This method is quite successful to deliver highly sterically crowded bi-aryls with dense functionalities on the aromatic rings.
Fe-catalyzed regiodivergent [1,2]-shift of α-aryl aldehydes
Gutierrez-Bonet, Alvaro,Flores-Gaspar, Areli,Martin, Ruben
, p. 12576 - 12579 (2013/09/23)
An Fe-catalyzed conversion of aldehydes to ketones via [1,2]-shift has been developed. This skeletal rearrangement shows a wide substrate scope and chemoselectivity profile while exhibiting an excellent [1,2]-aryl or [1,2]-alkyl shift selectivity that is easily switched by electronic effects.
Cobalt-catalyzed cross-coupling reactions of heterocyclic chlorides with arylmagnesium halides and of polyfunctionalized arylcopper reagents with aryl bromides, chlorides, fluorides and tosylates
Korn, Tobias J.,Schade, Matthias A.,Cheemala, Murthy N.,Wirth, Stefan,Guevara, Simon A.,Cahiez, Gerard,Knochel, Paul
, p. 3547 - 3574 (2008/03/14)
A range of aromatic organocopper or organomagnesium compounds undergo smooth cross-coupling reactions with aryl bromides, chlorides, fluorides and tosylates, leading to polyfunctionalized aromatics or heterocycles in the presence of cobalt salts (5-7.5 mol%) as catalysts. Very mild reaction conditions are needed and, in the case of cross-coupling with organocopper compounds, Bu4NI (1 equiv) and 4-fluorostyrene (20 mol%) are essential as promoters for successful couplings. Georg Thieme Verlag Stuttgart.
