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6-Methyl-2-phenylbenzoic acid, also known as tolfenamic acid, is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, fever, and inflammation. It works by inhibiting the production of prostaglandins, which are substances in the body that cause pain and inflammation.
Used in Pharmaceutical Industry:
6-Methyl-2-phenylbenzoic acid is used as an anti-inflammatory agent for its ability to reduce pain, fever, and inflammation. It is commonly used to treat conditions such as rheumatoid arthritis, osteoarthritis, and menstrual pain.
Used in Pain Management:
6-Methyl-2-phenylbenzoic acid is used as a pain reliever for its effectiveness in alleviating acute pain. It is often prescribed as a short-term treatment for conditions that cause severe discomfort.
Used in Topical Medications:
6-Methyl-2-phenylbenzoic acid is used as an active ingredient in topical formulations for its ability to provide localized relief from pain and inflammation.
Used with Caution in Individuals with Gastrointestinal Issues:
6-Methyl-2-phenylbenzoic acid should be used with caution in individuals with a history of gastrointestinal ulcers or bleeding, as it may exacerbate these conditions.
Used with Caution in Individuals with Liver and Kidney Issues:
6-Methyl-2-phenylbenzoic acid may have adverse effects on the liver and kidneys, and should be used with caution in individuals with pre-existing liver or kidney conditions.
Used with Consultation of Healthcare Professional:
It is important to consult a healthcare professional before using 6-methyl-2-phenylbenzoic acid, as it may interact with other medications and have potential side effects.

92254-02-9

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92254-02-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 92254-02-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,2,5 and 4 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 92254-02:
(7*9)+(6*2)+(5*2)+(4*5)+(3*4)+(2*0)+(1*2)=119
119 % 10 = 9
So 92254-02-9 is a valid CAS Registry Number.

92254-02-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-methyl-6-phenylbenzoic acid

1.2 Other means of identification

Product number -
Other names 6-METHYL-2-PHENYLBENZOIC ACID

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:92254-02-9 SDS

92254-02-9Relevant academic research and scientific papers

Palladium-Catalyzed Direct C(sp2)-H ortho-Arylation of Anilides Using 2-Aminophenylpyrazole as the Directing Group

Shen, Yuning,Cindy Lee, Wan-Chen,Gutierrez, David A.,Li, Jie Jack

, p. 11620 - 11625 (2017/11/10)

Palladium-catalyzed ortho-arylation of anilides was achieved using 2-aminophenyl-1H-pyrazole (2-APP) as a new directing group. Using Pd(OAc)2 as the catalyst and AgO as the promoter, mono- and diarylation of anilides were realized in up to 89% isolated yield. Further manipulation of the arylation product may be accomplished by a 2-step sequence involving an acidic hydrolysis of the methylated amide. More interestingly, in the presence of K2CO3, tandem C-C/C-N cyclization products were obtained for a couple of substrates.

ortho-C?H Arylation of Benzoic Acids with Aryl Bromides and Chlorides Catalyzed by Ruthenium

Biafora, Agostino,Krause, Thilo,Hackenberger, Dagmar,Belitz, Florian,Goo?en, Lukas J.

supporting information, p. 14752 - 14755 (2016/11/23)

A system consisting of catalytic amounts of [(p-cym)RuCl2]2/PEt3?HBF4, K2CO3as the base, and NMP as the solvent efficiently mediates the ortho-C?H arylation of benzoic acids with aryl bromides at 100 °C. Replacing the phosphine ligand with the amino acid dl-pipecolinic acid enables the analogous transformation with aryl chlorides. The key advantage of this broadly applicable transformation is the use of an inexpensive ruthenium catalyst in combination with simple carboxylates as directing groups, which can either be tracelessly removed or used as anchor points for decarboxylative ipso substitutions.

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