92256-74-1 Usage
General Description
2-Acetamido-3-(6-methoxy-1H-indol-3-yl)propanoic acid is a chemical compound with the molecular formula C14H16N2O4. It is a derivative of indole and is a potential inhibitor of the enzyme tryptophan 2,3-dioxygenase (TDO), which plays a role in the metabolism of the amino acid tryptophan. 2-acetaMido-3-(6-Methoxy-1H-indol-3-yl)propanoic acid has shown potential as a therapeutic agent for the treatment of cancer, as the inhibition of TDO can lead to an increase in tryptophan levels, which in turn can have anti-tumor effects. Additionally, 2-acetamido-3-(6-methoxy-1H-indol-3-yl)propanoic acid has also been studied for its potential anti-inflammatory and neuroprotective effects. Its precise mechanism of action and potential clinical applications are still under investigation.
Check Digit Verification of cas no
The CAS Registry Mumber 92256-74-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,2,5 and 6 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 92256-74:
(7*9)+(6*2)+(5*2)+(4*5)+(3*6)+(2*7)+(1*4)=141
141 % 10 = 1
So 92256-74-1 is a valid CAS Registry Number.
92256-74-1Relevant academic research and scientific papers
The facile synthesis of a series of tryptophan derivatives
Blaser, Georg,Sanderson, John M.,Batsanov, Andrei S.,Howard, Judith A.K.
, p. 2795 - 2798 (2008/09/19)
This study reports a facile method for the synthesis of a variety of 5- and 6-substituted tryptophan derivatives that are difficult to prepare using alternative enzymatic approaches. Acylation of an activated amino acid, derived from serine in situ, is coupled with an enzymatic resolution step to furnish enantiopure analogues bearing a range of electron withdrawing and releasing substituents. Isolation of a dehydroalanine derivative as a by-product from some reactions provides some insights into the likely mechanism of the reaction.
