92264-20-5

Upstream product

• 92264-23-8 (2R,4S)-3-Benzyl-8,9-dimethoxy-2,4-dimethyl-1,3,4,6-tetrahydro-2H-5-oxa-3-aza-benzo[c]chrysene 
• 22273-57-0 4,5-dimethoxy-2-methyl-naphthalene 
• 92264-19-2 (1S,3R)-2-Benzyl-8-(1-bromo-4,5-dimethoxy-naphthalen-2-ylmethoxy)-1,3-dimethyl-1,2,3,4-tetrahydro-isoquinoline 
• 92264-18-1 (1S,3R)-2-Benzyl-1,3-dimethyl-1,2,3,4-tetrahydro-isoquinolin-8-ol; hydrobromide 
• 82958-26-7 8-Methoxy-1,3-dimethyl-isoquinoline; hydrobromide 
• 92264-17-0 (1S,3R)-2-Benzyl-8-methoxy-1,3-dimethyl-1,2,3,4-tetrahydro-isoquinoline 
• 92264-14-7 1-bromo-2-(bromomethyl)-4,5-dimethoxynaphthalene 
• 92264-15-8 (1S,3R)-8-Methoxy-1,3-dimethyl-1,2,3,4-tetrahydro-isoquinoline 
• 100-39-0 benzyl bromide 

Relevant academic research and scientific papers

A FIRST AND GENERAL RULE TO NAPHTHYLISOQUINOLINE ALKALOIDS: THE TOTAL SYNTHESIS OF O-METHYL-TETRADEHYDRO-TRIOPHYOPHYLLINE

The first total synthesis of a naphtylisoquinoline alkaloid is described.The required ortho selective mixed coupling of the alkaloid moieties 2 and 6 is achieved intramolecularly by the assistance of a reversibly thrown benzylether type auxiliary bridge.