92265-07-1

Upstream product

• 4491-47-8 2-phenyl-4-isopropylidene-5(4H)oxazolone 
• 98-88-4 benzoyl chloride 
• 16369-05-4 valinol 
• 227080-13-9 2-(4-bromo-phenyl)-4-isopropyl-4,5-dihydro-oxazole 
• 4380-77-2 O-phenylbenzohydroxamic acid 

Downstream Products

• 916685-60-4 (S)-2-benzamido-3-methylbutyl benzoate 
• 1492-13-3 (2R)-2-(benzoylamino)-3-methylbutyric acid methyl ester 
• 1492-13-3 N-benzoyl-L-valine methyl ester 
• 479672-27-0 N-(1-formyl-2-methylpropyl)benzamide 
• 1218937-28-0 C₁₂H₁₅NS 

Relevant academic research and scientific papers

Catalytic Alkene Difunctionalization via Imidate Radicals

The first catalytic strategy to harness imidate radicals has been developed. This approach enables alkene difunctionalization of allyl alcohols by photocatalytic reduction of their oxime imidates. The ensuing imidate radicals undergo consecutive intra- and intermolecular reactions to afford (i) hydroamination, (ii) aminoalkylation, or (iii) aminoarylation, via three distinct radical mechanisms. The broad scope and utility of this catalytic method for imidate radical reactivity is presented, along with comparisons to other N-centered radicals and complementary, closed-shell imidate pathways.

A facile synthesis of 2,4-disubstituted thiazoles using MnO2

Structurally diverse thiazoles with electron-donating and electron-withdrawing groups were conveniently synthesized through manganese dioxide (MnO2) oxidation of the corresponding thiazolines. The effect of substitution at the 2- and 4-positions was investigated. The desired thiazoles with aryl or vinyl substitutions at the 2- or 4-position can be obtained in good to excellent yields.