923033-01-6Relevant academic research and scientific papers
Umpolung of protons from H2O: A metal-free chemoselective reduction of carbonyl compounds: Via B2pin2/H2O systems
Xuan, Qingqing,Zhao, Cong,Song, Qiuling
supporting information, p. 5140 - 5144 (2017/07/11)
H2O is routinely described as a proton donor, however, in the presence of diboron compounds, the umpolung reaction of H2O under metal-free conditions was successfully developed, which could afford hydride species, leading to a highly efficient and chemoselective reduction of CO bonds. This strategy exhibits excellent chemoselectivities toward carbonyl groups in the presence of ester, olefin, halogen, thioether, sulfonyl, cyano as well as heteroaromatic groups.
N-(ARYLAMINO)-SULFONAMIDE INHIBITORS OF MEK
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Page/Page column 94; 95, (2008/06/13)
This invention concerns N-(2-arylamino) aryl sulfonamides, which are inhibitors of MEK and are useful in treatment of cancer and other hyperproliferative diseases.
