923036-27-5 Usage
Chemical Structure
1-benzyl-3-((Methoxycarbonyl)amino)-4-methylpyridin-1-ium bromide
Family
Benzyl-3-pyridinylalanine derivatives
Target
Cyclin-dependent kinases (CDKs) 1, 2, and 5
Enzyme Role
Regulate cell cycle progression
Dysregulation
Associated with cancer development and growth
Preclinical Studies
Shown potential for treating various types of cancer (breast, lung, prostate)
Mechanism of Action
Selective CDK inhibitor
Potential
Development of new targeted cancer therapies
Current Status
Further research needed to understand mechanism of action and therapeutic potential
Check Digit Verification of cas no
The CAS Registry Mumber 923036-27-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,3,0,3 and 6 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 923036-27:
(8*9)+(7*2)+(6*3)+(5*0)+(4*3)+(3*6)+(2*2)+(1*7)=145
145 % 10 = 5
So 923036-27-5 is a valid CAS Registry Number.
923036-27-5Relevant academic research and scientific papers
PIPERIDINE INHIBITORS OF JANUS KINASE 3
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Page/Page column 50, (2010/11/05)
The present invention relates to a new piperidine inhibitors of Janus Kinase 3 activity, pharmaceutical compositions thereof, and methods of use there-of.
PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES; THEIR INTERMEDIATES AND SYNTHESIS
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Page/Page column 18-19, (2010/11/25)
This invention relates to methods and intermediates useful for the synthesis of pyrrolo [2,3-d] pyrimidine compounds. Specifically novel synthetic methods and intermediates for the synthesis of 3- {(3R, 4R)-4-methyl-(7H-pyrrolo[2,3-d] pyrimidin-4-yl)-amino}-piperidin-1-yl)-3-oxo-propionitrile and its corresponding citrate salt are disclosed.
