92304-61-5

Basic information

• Product Name: Pyrazole-3(or 5)-carboxylic acid, 4-propyl- (7CI)
• Synonyms: Pyrazole-3(or 5)-carboxylic acid, 4-propyl- (7CI)
• CAS NO: 92304-61-5
• Molecular Formula: C7H10N2O2
• Molecular Weight: 154.1665
• Product Categories: GLYCINESCAFFOLD
• Mol File: 92304-61-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 358.7±22.0 °C(Predicted)
• Appearance: /
• Density: 1 +-.0.06 g/cm3(Predicted)
• PKA: 15.75±0.50(Predicted)
• CAS DataBase Reference: Pyrazole-3(or 5)-carboxylic acid, 4-propyl- (7CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrazole-3(or 5)-carboxylic acid, 4-propyl- (7CI)(92304-61-5)
• EPA Substance Registry System: Pyrazole-3(or 5)-carboxylic acid, 4-propyl- (7CI)(92304-61-5)

Safety Data

• Hazardous Substances Data: 92304-61-5(Hazardous Substances Data)

Upstream product

• 1552-67-6 ethyl hex-2-enoate 
• 92939-26-9 4-propyl-1H-pyrazole-3-carboxylic acid ethyl ester 

Relevant articles and documents

Preparations of 4-substituted 3-carboxypyrazoles

The scopes of three synthetic methods reported for the preparation of an array of 3-pyrazolecarboxylates featuring substituents on position 4 were investigated. The first one is based on the potassium permanganate oxidation of methylpyrazoles. The second starts with the condensation between DMF dimethylacetal and ethyl pyruvate and is followed by the addition of hydrazine hydrochloride. The last one makes use of the cycloaddition of diazomethane on acrylate esters followed by a bromine-based oxidative rearrangement into 4-substituted 3-pyrazole esters.