923276-78-2

Basic information

• Product Name: 2-Oxazolidinone, 5-(azidomethyl)-
• CAS NO: 923276-78-2
• Molecular Formula: C4H6N4O2
• Molecular Weight: 142.117
• Mol File: 923276-78-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Oxazolidinone, 5-(azidomethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxazolidinone, 5-(azidomethyl)-(923276-78-2)
• EPA Substance Registry System: 2-Oxazolidinone, 5-(azidomethyl)-(923276-78-2)

Safety Data

• Hazardous Substances Data: 923276-78-2(Hazardous Substances Data)

Upstream product

• 22625-57-6 5-(chloromethyl)-1,3-oxazolidin-2-one 
• 590-28-3 potassium cyanate 
• 51275-91-3 1-azido-3-chloro-propan-2-ol 

Downstream Products

• 119736-09-3 5-(S)-aminomethyloxazolidinone 

Relevant articles and documents

Direct Palladium-Catalyzed β-Arylation of Lactams

A direct and catalytic method is reported here for β-arylation of N-protected lactams with simple aryl iodides. The transformation is enabled by merging soft enolization of lactams, palladium-catalyzed desaturation, Ar?X bond activation, and aryl conjugate addition. The reaction is operated under mild reaction conditions, is scalable, and is chemoselective. Application of this method to concise syntheses of pharmaceutically relevant compounds is demonstrated.

DMAP-catalyzed synthesis of 2-oxazolidinones from corresponding halohydrins using KOCN/DMF

We report facile and simple synthesis of a variety of 2-oxazolidinones from the corresponding halohydrins by reaction with KOCN in DMF catalyzed by DMAP. DMAP and temperature play key roles in enriching the yield of 2-oxazolidinones. A few examples in this Letter are applicable to pharmaceutically important processes.