92339-84-9 Usage
Uses
Used in Pharmaceutical Industry:
8-Aminoquinoline N-Oxide is used as an antimalarial agent for its potential to combat malaria, a disease caused by Plasmodium parasites. Its unique chemical structure allows it to target and disrupt essential processes within the parasite, offering a promising therapeutic approach to treating this widespread illness.
Used in Coordination Chemistry:
8-Aminoquinoline N-Oxide serves as a ligand in coordination chemistry, where it forms complexes with metal ions. These complexes exhibit interesting properties and can be used in various applications, such as catalysis, sensing, and materials science.
Used in Organic Electronics:
8-Aminoquinoline N-Oxide is utilized in the development of organic electronic devices, such as organic light-emitting diodes (OLEDs) and organic field-effect transistors (OFETs). Its electronic properties and compatibility with other organic materials make it a valuable component in these advanced technologies.
Used in Cancer Research:
8-Aminoquinoline N-Oxide is studied for its potential cytotoxic and anticancer properties. Its ability to interfere with cancer cell growth and proliferation makes it a candidate for further research in the development of novel anticancer drugs.
Used in Materials Science:
8-Aminoquinoline N-Oxide is explored for its potential applications in materials science, where its unique properties can be harnessed to create new materials with specific characteristics, such as improved conductivity, stability, or responsiveness to external stimuli.
Check Digit Verification of cas no
The CAS Registry Mumber 92339-84-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,3,3 and 9 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 92339-84:
(7*9)+(6*2)+(5*3)+(4*3)+(3*9)+(2*8)+(1*4)=149
149 % 10 = 9
So 92339-84-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H8N2O/c10-8-5-1-3-7-4-2-6-11(12)9(7)8/h1-6H,10H2
92339-84-9Relevant academic research and scientific papers
Co(III)-Catalyzed C-H Amidation of Nitrogen-Containing Heterocycles with Dioxazolones under Mild Conditions
Dhiman, Ankit Kumar,Thakur, Ankita,Kumar, Inder,Kumar, Rakesh,Sharma, Upendra
, p. 9244 - 9254 (2020/08/14)
A cobalt(III)-catalyzed C-8 selective C-H amidation of quinoline N-oxide using dioxazolone as an amidating reagent under mild conditions is disclosed. The reaction proceeds efficiently with excellent functional group compatibility. The utility of the current method is demonstrated by gram scale synthesis of C-8 amide quinoline N-oxide and by converting this amidated product into functionalized quinolines. Furthermore, the developed catalytic method is also applicable for C-7 amidation of N-pyrimidylindolines and ortho-amidation of benzamides.
Regioselective introduction of heteroatoms at the C-8 position of quinoline N-oxides: Remote C-H activation using N-oxide as a stepping stone
Hwang, Heejun,Kim, Jinwoo,Jeong, Jisu,Chang, Sukbok
supporting information, p. 10770 - 10776 (2014/08/18)
Reported herein is the metal-catalyzed regioselective C-H functionalization of quinoline N-oxides at the 8-position: direct iodination and amidation were developed using rhodium and iridium catalytic systems, respectively. Mechanistic study of the amidation revealed that the unique regioselectivity is achieved through the smooth formation of N-oxide-chelated iridacycle and that an acid additive plays a key role in the rate-determining protodemetalation step. While this approach of remote C-H activation using N-oxide as a directing group could readily be applied to a wide range of heterocyclic substrates under mild conditions with high functional group tolerance, an efficient synthesis of zinquin ester (a fluorescent zinc indicator) was demonstrated.
